Acyclovir/pharmacology; Antiviral Agents/pharmacology; Exodeoxyribonucleases/antagonists & inhibitors; Foscarnet/pharmacology; Herpesvirus 1, Human/enzymology; Models, Molecular; Nucleic Acid Synthesis Inhibitors/pharmacology; Viral Proteins/antagonists & inhibitors; Acyclovir/chemistry; Acyclovir/metabolism; Antiviral Agents/chemistry; Antiviral Agents/metabolism; Catalytic Domain; DNA, Single-Stranded/chemistry; DNA, Single-Stranded/metabolism; DNA-Directed DNA Polymerase/chemistry; DNA-Directed DNA Polymerase/genetics; DNA-Directed DNA Polymerase/metabolism; Exodeoxyribonucleases/chemistry; Exodeoxyribonucleases/genetics; Exodeoxyribonucleases/metabolism; Foscarnet/chemistry; Foscarnet/metabolism; Herpesvirus 1, Human/drug effects; Hydrolysis/drug effects; Kinetics; Molecular Structure; Nucleic Acid Synthesis Inhibitors/chemistry; Nucleic Acid Synthesis Inhibitors/metabolism; Recombinant Proteins/chemistry; Recombinant Proteins/metabolism; Ribonucleotides/chemistry; Ribonucleotides/metabolism; Substrate Specificity; Viral Proteins/chemistry; Viral Proteins/genetics; Viral Proteins/metabolism