Involvement of Gaucher Disease Mutations in Parkinson Disease.

Vilageliu, Lluisa; Grinberg, Daniel

Vilageliu, Lluisa; Grinberg, Daniel.

Affiliation

Vilageliu L; Department of Genetics, Faculty of Biology, Universitat de Barcelona, IBUB, CIBERER, Barcelona, Spain.
Grinberg D; Departament de Genetica, Facultat de Biología, Universitat de Barcelona, Av. Diagonal 643, E-08028 Barcelona, Spain.

Curr Protein Pept Sci ; 18(7): 758-764, 2017.

Article in En | MEDLINE | ID: mdl-26965692

Subject(s)

Gaucher Disease/genetics; Glucosylceramidase/genetics; Mutation; Parkinson Disease/genetics; alpha-Synuclein/genetics; Alleles; Gaucher Disease/complications; Gaucher Disease/metabolism; Gaucher Disease/pathology; Gene Expression; Gene Frequency; Glucosylceramidase/metabolism; Humans; Lysosomes/drug effects; Lysosomes/metabolism; Lysosomes/pathology; Parkinson Disease/complications; Parkinson Disease/metabolism; Parkinson Disease/pathology; Saposins/pharmacology; alpha-Synuclein/metabolism

Key words

E326K; GBA mutations; Gaucher disease; L444P; Parkinson disease; saposin C; α-synuclein

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Alpha-Synuclein / Gaucher Disease / Glucosylceramidase / Mutation Limits: Humans Language: En Journal: Curr Protein Pept Sci Year: 2017 Document type: Article

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