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Antibody-Mediated Insulin Resistance: When Insulin and Insulin Receptor Act as Autoantigens in Humans.
Liminet, Christelle; Vouillarmet, Julien; Chikh, Karim; Disse, Emmanuel.
Affiliation
  • Liminet C; Department of Endocrinology, Diabetology and Nutrition, Groupement Hospitalier Lyon Sud, Fédération Hospitalo-Universitaire DO-IT, Hospices Civils de Lyon, Lyon, France; University Claude Bernard Lyon 1, Lyon, France.
  • Vouillarmet J; Department of Endocrinology, Diabetology and Nutrition, Groupement Hospitalier Lyon Sud, Fédération Hospitalo-Universitaire DO-IT, Hospices Civils de Lyon, Lyon, France. Electronic address: julien.vouillarmet@chu-lyon.fr.
  • Chikh K; University Claude Bernard Lyon 1, Lyon, France; Department of Biochemistry, Groupement Hospitalier Lyon Sud, Hospices Civils de Lyon, Lyon, France.
  • Disse E; Department of Endocrinology, Diabetology and Nutrition, Groupement Hospitalier Lyon Sud, Fédération Hospitalo-Universitaire DO-IT, Hospices Civils de Lyon, Lyon, France; University Claude Bernard Lyon 1, Lyon, France.
Can J Diabetes ; 40(5): 462-465, 2016 Oct.
Article in En | MEDLINE | ID: mdl-27062110
ABSTRACT
We report the case of a patient with diabetes presenting a severe insulin-resistance syndrome due to the production of insulin autoantibodies by a lymphocytic lymphoma. We describe the various mechanisms leading to the production of insulin autoantibodies and insulin receptor autoantibodies and review the therapeutic possibilities.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autoantigens / Insulin Resistance / Leukemia, Lymphocytic, Chronic, B-Cell / Diabetes Mellitus Limits: Aged80 / Humans / Male Language: En Journal: Can J Diabetes Year: 2016 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autoantigens / Insulin Resistance / Leukemia, Lymphocytic, Chronic, B-Cell / Diabetes Mellitus Limits: Aged80 / Humans / Male Language: En Journal: Can J Diabetes Year: 2016 Document type: Article