The possible role of mRNA expression changes of GH/IGF-1/insulin axis components in subcutaneous adipose tissue in metabolic disturbances of patients with acromegaly.

Touskova, V; Klouckova, J; Durovcova, V; Lacinova, Z; Kavalkova, P; Trachta, P; Kosak, M; Mraz, M; Haluzikova, D; Hana, V; Marek, J; Krsek, M; Haluzik, M

Touskova, V; Klouckova, J; Durovcova, V; Lacinova, Z; Kavalkova, P; Trachta, P; Kosak, M; Mraz, M; Haluzikova, D; Hana, V; Marek, J; Krsek, M; Haluzik, M.

Affiliation

Touskova V; Third Department of Medicine, General University Hospital and First Faculty of Medicine, Charles University, Prague, Czech Republic, Institute of Endocrinology, Prague, Czech Republic. mhalu@lf1.cuni.cz.

Physiol Res ; 65(3): 493-503, 2016 07 18.

Article in En | MEDLINE | ID: mdl-27070751

Subject(s)

Acromegaly/metabolism; Class Ia Phosphatidylinositol 3-Kinase/blood; Human Growth Hormone/metabolism; Insulin Resistance; Insulin-Like Growth Factor Binding Protein 3/metabolism; Subcutaneous Fat/metabolism; Adult; Case-Control Studies; Female; Human Growth Hormone/blood; Humans; Insulin/blood; Insulin-Like Growth Factor I/metabolism; Male; Middle Aged; RNA, Messenger/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Acromegaly / Insulin Resistance / Insulin-Like Growth Factor Binding Protein 3 / Human Growth Hormone / Subcutaneous Fat / Class Ia Phosphatidylinositol 3-Kinase Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Physiol Res Year: 2016 Document type: Article

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