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Pulsatile blood flow in total cavopulmonary connection: a comparison between Y-shaped and T-shaped geometry.
Rajabzadeh-Oghaz, Hamidreza; Firoozabadi, Bahar; Saidi, Mohammad Said; Monjezi, Mojdeh; Navabi Shirazi, Mohammad Ali; Malakan Rad, Elaheh.
Affiliation
  • Rajabzadeh-Oghaz H; Department of Mechanical Engineering, Sharif University of Technology, Tehran, Iran.
  • Firoozabadi B; Department of Mechanical Engineering, Sharif University of Technology, Tehran, Iran. Firoozabadi@sharif.edu.
  • Saidi MS; Department of Mechanical Engineering, Sharif University of Technology, Tehran, Iran.
  • Monjezi M; Department of Mechanical Engineering, Sharif University of Technology, Tehran, Iran.
  • Navabi Shirazi MA; Department of Pediatric Cardiac Surgery, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Malakan Rad E; Department of Pediatric Cardiology, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Med Biol Eng Comput ; 55(2): 213-224, 2017 Feb.
Article in En | MEDLINE | ID: mdl-27108290
Single-ventricle anomaly is a hereditary heart disease that is characterized by anatomical malformations. The main consequence of this malformation is desaturated blood flow, which without proper treatment increases the risk of death. The classical treatment is based on a three-stage palliative procedure which should begin from the first few days of patient's life. The final stage is known as Fontan procedure, in which inferior vena cava is directly connected to pulmonary arteries without going through the ventricle. This connection is called total cavopulmonary connection (TCPC). After surgery, the single ventricle supplies adequate and saturated systemic blood flow to the body; however, TCPC contains low pressure and low flow pulsatility. To overcome this problem, a new method is proposed wherein pulsatile blood will be directed to the TCPC through the stenosed main pulmonary artery. In this study, through the use of Computational Fluid Dynamics, T-shaped (MRI-based) and Y-shaped (computer-generated) geometries are compared in order to determine the influence of this modification on pulsation of blood flow as well as energy loss in pulmonary arteries. The results indicate that energy loss in Y-shaped geometry is far less than T-shaped geometry, while the difference in flow pulsatility is insignificant.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Artery / Fontan Procedure / Coronary Circulation / Heart Ventricles / Models, Cardiovascular Limits: Child / Female / Humans Language: En Journal: Med Biol Eng Comput Year: 2017 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Artery / Fontan Procedure / Coronary Circulation / Heart Ventricles / Models, Cardiovascular Limits: Child / Female / Humans Language: En Journal: Med Biol Eng Comput Year: 2017 Document type: Article