Repeated rituximab-induced serum sickness with anaphylaxis.
Rinsho Ketsueki
; 57(6): 771-3, 2016 06.
Article
in Ja
| MEDLINE
| ID: mdl-27384859
ABSTRACT
We describe a patient who developed repeated rituximab-induced serum sickness (RISS) followed by anaphylaxis soon after the third administration of rituximab at relapse. A 65-year-old woman with Sjögren's syndrome and relapsed mucosal associated lymphoma tissue (MALT) lymphoma of the lung underwent rituximab monotherapy (375 mg/m(2)/week). Several days after the second exposure to rituximab, she developed a rash, fever, and arthralgia. These symptoms showed relief, but a severe anaphylactic reaction occurred when she was treated with rituximab for the third time. Although a rare complication in patients with lymphoma, clinicians should be aware of RISS symptoms and avoid repeatedly administering rituximab to such patients.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Serum Sickness
/
Rituximab
/
Anaphylaxis
/
Antineoplastic Agents
Limits:
Aged
/
Female
/
Humans
Language:
Ja
Journal:
Rinsho Ketsueki
Year:
2016
Document type:
Article