A Systems Model for Ursodeoxycholic Acid Metabolism in Healthy and Patients With Primary Biliary Cirrhosis.

Zuo, P; Dobbins, R L; O'Connor-Semmes, R L; Young, M A

Zuo, P; Dobbins, R L; O'Connor-Semmes, R L; Young, M A.

Affiliation

Zuo P; PAREXEL International, Durham, North Carolina, USA.
Dobbins RL; Cempra Pharmaceuticals, Chapel Hill, North Carolina, USA.
O'Connor-Semmes RL; PAREXEL International, Durham, North Carolina, USA.
Young MA; PAREXEL International, Durham, North Carolina, USA.

CPT Pharmacometrics Syst Pharmacol ; 5(8): 418-26, 2016 08.

Article in En | MEDLINE | ID: mdl-27537780

Subject(s)

Cholagogues and Choleretics/metabolism; Liver Cirrhosis, Biliary/metabolism; Systems Analysis; Ursodeoxycholic Acid/metabolism; Administration, Oral; Bile Acids and Salts/metabolism; Cholagogues and Choleretics/administration & dosage; Databases, Factual/statistics & numerical data; Humans; Ileum/drug effects; Ileum/metabolism; Liver Cirrhosis, Biliary/drug therapy; Random Allocation; Ursodeoxycholic Acid/administration & dosage

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Systems Analysis / Ursodeoxycholic Acid / Cholagogues and Choleretics / Liver Cirrhosis, Biliary Type of study: Clinical_trials / Prognostic_studies Limits: Humans Language: En Journal: CPT Pharmacometrics Syst Pharmacol Year: 2016 Document type: Article

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