Glycopeptide Antibiotic To Overcome the Intrinsic Resistance of Gram-Negative Bacteria.

Yarlagadda, Venkateswarlu; Manjunath, Goutham B; Sarkar, Paramita; Akkapeddi, Padma; Paramanandham, Krishnamoorthy; Shome, Bibek R; Ravikumar, Raju; Haldar, Jayanta

Yarlagadda, Venkateswarlu; Manjunath, Goutham B; Sarkar, Paramita; Akkapeddi, Padma; Paramanandham, Krishnamoorthy; Shome, Bibek R; Ravikumar, Raju; Haldar, Jayanta.

Affiliation

Yarlagadda V; Chemical Biology and Medicinal Chemistry Laboratory, New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research , Jakkur, Bengaluru 560064, Karnataka, India.
Manjunath GB; Chemical Biology and Medicinal Chemistry Laboratory, New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research , Jakkur, Bengaluru 560064, Karnataka, India.
Sarkar P; Chemical Biology and Medicinal Chemistry Laboratory, New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research , Jakkur, Bengaluru 560064, Karnataka, India.
Akkapeddi P; Chemical Biology and Medicinal Chemistry Laboratory, New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research , Jakkur, Bengaluru 560064, Karnataka, India.
Paramanandham K; National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI) Yelahanka , Bengaluru 560064, Karnataka, India.
Shome BR; National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI) Yelahanka , Bengaluru 560064, Karnataka, India.
Ravikumar R; Department of Neuromicrobiology, National Institute of Mental Health and Neuro Sciences , Hosur Road, Bengaluru 560029, Karnataka, India.
Haldar J; Chemical Biology and Medicinal Chemistry Laboratory, New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research , Jakkur, Bengaluru 560064, Karnataka, India.

ACS Infect Dis ; 2(2): 132-9, 2016 02 12.

Article in En | MEDLINE | ID: mdl-27624964

Subject(s)

Anti-Bacterial Agents/pharmacology; Drug Resistance, Multiple, Bacterial/drug effects; Gram-Negative Bacterial Infections/drug therapy; Gram-Negative Bacterial Infections/microbiology; Vancomycin/pharmacology; Acinetobacter baumannii/drug effects; Animals; Cell Membrane/drug effects; Cell Membrane/microbiology; Disease Models, Animal; Female; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Pseudomonas aeruginosa/drug effects; Structure-Activity Relationship; Vancomycin/analogs & derivatives

Key words

Gram-negative bacteria; antibacterial activity; glycopeptide antibiotics; intrinsic antibiotic resistance; vancomycin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vancomycin / Gram-Negative Bacterial Infections / Drug Resistance, Multiple, Bacterial / Anti-Bacterial Agents Limits: Animals Language: En Journal: ACS Infect Dis Year: 2016 Document type: Article

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