New and Old Hot Drug Targets in Tuberculosis.

Chiarelli, Laurent Roberto; Mori, Giorgia; Esposito, Marta; Orena, Beatrice Silvia; Pasca, Maria Rosalia

Chiarelli, Laurent Roberto; Mori, Giorgia; Esposito, Marta; Orena, Beatrice Silvia; Pasca, Maria Rosalia.

Affiliation

Pasca MR; Department of Biology and Biotechnology Lazzaro Spallanzani, University of Pavia, via Ferrata 1, Pavia, Italy. mariarosalia.pasca@unipv.it.

Curr Med Chem ; 23(33): 3813-3846, 2016.

Article in En | MEDLINE | ID: mdl-27666933

Subject(s)

Antitubercular Agents/therapeutic use; Bacterial Proteins/antagonists & inhibitors; Tuberculosis/drug therapy; Antitubercular Agents/chemistry; Antitubercular Agents/pharmacology; Bacterial Proteins/metabolism; Binding Sites; DNA Gyrase/chemistry; DNA Gyrase/metabolism; DNA-Directed RNA Polymerases/antagonists & inhibitors; DNA-Directed RNA Polymerases/metabolism; Drug Design; Humans; Molecular Docking Simulation; Mycobacterium tuberculosis/drug effects; Mycobacterium tuberculosis/metabolism; Oxidoreductases/antagonists & inhibitors; Oxidoreductases/metabolism; Tuberculosis/microbiology

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Collection: 01-internacional Health context: 2_ODS3 / 3_ND Database: MEDLINE Main subject: Bacterial Proteins / Tuberculosis / Antitubercular Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Curr Med Chem Year: 2016 Document type: Article

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