FANCD2 Facilitates Replication through Common Fragile Sites.

Madireddy, Advaitha; Kosiyatrakul, Settapong T; Boisvert, Rebecca A; Herrera-Moyano, Emilia; García-Rubio, María L; Gerhardt, Jeannine; Vuono, Elizabeth A; Owen, Nichole; Yan, Zi; Olson, Susan; Aguilera, Andrés; Howlett, Niall G; Schildkraut, Carl L

Madireddy, Advaitha; Kosiyatrakul, Settapong T; Boisvert, Rebecca A; Herrera-Moyano, Emilia; García-Rubio, María L; Gerhardt, Jeannine; Vuono, Elizabeth A; Owen, Nichole; Yan, Zi; Olson, Susan; Aguilera, Andrés; Howlett, Niall G; Schildkraut, Carl L.

Affiliation

Madireddy A; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address: advaitha@gmail.com.
Kosiyatrakul ST; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Boisvert RA; Department of Cell and Molecular Biology, University of Rhode Island, Kingston, RI 02881, USA.
Herrera-Moyano E; Centro Andaluz de Biología Molecular y Medicina Regenerativa, Universidad de Sevilla, 41092 Seville, Spain.
García-Rubio ML; Centro Andaluz de Biología Molecular y Medicina Regenerativa, Universidad de Sevilla, 41092 Seville, Spain.
Gerhardt J; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Vuono EA; Department of Cell and Molecular Biology, University of Rhode Island, Kingston, RI 02881, USA.
Owen N; Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, OR 97239, USA.
Yan Z; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Olson S; Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, OR 97239, USA.
Aguilera A; Centro Andaluz de Biología Molecular y Medicina Regenerativa, Universidad de Sevilla, 41092 Seville, Spain.
Howlett NG; Department of Cell and Molecular Biology, University of Rhode Island, Kingston, RI 02881, USA.
Schildkraut CL; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address: schildkr@aecom.yu.edu.

Mol Cell ; 64(2): 388-404, 2016 10 20.

Article in En | MEDLINE | ID: mdl-27768874

Subject(s)

Chromosome Fragile Sites; DNA Replication; DNA/genetics; Fanconi Anemia Complementation Group D2 Protein/genetics; RNA/genetics; BRCA2 Protein/genetics; BRCA2 Protein/metabolism; Cell Line, Transformed; DNA/metabolism; Fanconi Anemia; Fanconi Anemia Complementation Group A Protein/genetics; Fanconi Anemia Complementation Group A Protein/metabolism; Fanconi Anemia Complementation Group D2 Protein/metabolism; Fanconi Anemia Complementation Group Proteins/genetics; Fanconi Anemia Complementation Group Proteins/metabolism; Fibroblasts/cytology; Fibroblasts/metabolism; Gene Expression; Genomic Instability; Herpesvirus 4, Human/genetics; Herpesvirus 4, Human/metabolism; Humans; Lymphocytes/cytology; Lymphocytes/metabolism; RNA/metabolism

Key words

DNA replication; DNA:RNA hybrids; Fanconi anemia; cancer; common fragile sites; genomic instability

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / RNA / Chromosome Fragile Sites / DNA Replication / Fanconi Anemia Complementation Group D2 Protein Type of study: Prognostic_studies Limits: Humans Language: En Journal: Mol Cell Year: 2016 Document type: Article

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