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Phosphoproteomic analysis reveals hyperactivation of mTOR/STAT3 and LCK/Calcineurin axes in pediatric early T-cell precursor ALL.
Serafin, V; Lissandron, V; Buldini, B; Bresolin, S; Paganin, M; Grillo, F; Andriano, N; Palmi, C; Cazzaniga, G; Marmiroli, S; Conter, V; Basso, G; Accordi, B.
Affiliation
  • Serafin V; Department of Woman's and Child's Health, University of Padova, Padova, Italy.
  • Lissandron V; Department of Woman's and Child's Health, University of Padova, Padova, Italy.
  • Buldini B; Department of Woman's and Child's Health, University of Padova, Padova, Italy.
  • Bresolin S; Department of Woman's and Child's Health, University of Padova, Padova, Italy.
  • Paganin M; Department of Woman's and Child's Health, University of Padova, Padova, Italy.
  • Grillo F; Department of Woman's and Child's Health, University of Padova, Padova, Italy.
  • Andriano N; Centro Ricerca Tettamanti, Department of Pediatrics, University of Milano-Bicocca, Fondazione MBBM, Monza, Italy.
  • Palmi C; Centro Ricerca Tettamanti, Department of Pediatrics, University of Milano-Bicocca, Fondazione MBBM, Monza, Italy.
  • Cazzaniga G; Centro Ricerca Tettamanti, Department of Pediatrics, University of Milano-Bicocca, Fondazione MBBM, Monza, Italy.
  • Marmiroli S; Department of Surgery, Medicine, Dentistry and Morphology, University of Modena and Reggio Emilia, Modena, Italy.
  • Conter V; Center of Hemato-Oncology, Department of Pediatrics, University of Milano-Bicocca, Fondazione MBBM, Ospedale San Gerardo, Monza, Italy.
  • Basso G; Department of Woman's and Child's Health, University of Padova, Padova, Italy.
  • Accordi B; Department of Woman's and Child's Health, University of Padova, Padova, Italy.
Leukemia ; 31(4): 1007-1011, 2017 04.
Article in En | MEDLINE | ID: mdl-28082737
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphorylation / Calcineurin / Lymphocyte Specific Protein Tyrosine Kinase p56(lck) / STAT3 Transcription Factor / Precursor Cells, T-Lymphoid / Precursor Cell Lymphoblastic Leukemia-Lymphoma / TOR Serine-Threonine Kinases Limits: Humans Language: En Journal: Leukemia Year: 2017 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphorylation / Calcineurin / Lymphocyte Specific Protein Tyrosine Kinase p56(lck) / STAT3 Transcription Factor / Precursor Cells, T-Lymphoid / Precursor Cell Lymphoblastic Leukemia-Lymphoma / TOR Serine-Threonine Kinases Limits: Humans Language: En Journal: Leukemia Year: 2017 Document type: Article