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Solvent-Responsive Molecularly Imprinted Nanogels for Targeted Protein Analysis in MALDI-TOF Mass Spectrometry.
Bertolla, Maddalena; Cenci, Lucia; Anesi, Andrea; Ambrosi, Emmanuele; Tagliaro, Franco; Vanzetti, Lia; Guella, Graziano; Bossi, Alessandra Maria.
Affiliation
  • Bertolla M; Department of Physics, University of Trento , Via Sommarive 14, 38123 Trento, Italy.
  • Cenci L; Department of Biotechnology, University of Verona , Strada Le Grazie 15, 37134 Verona, Italy.
  • Anesi A; Department of Physics, University of Trento , Via Sommarive 14, 38123 Trento, Italy.
  • Ambrosi E; Department of Molecular Sciences and Nanosystems, University Cà Foscari Venezia , Via Torino 155/b, 30173 Venice, Italy.
  • Tagliaro F; Department of Diagnostics and Public Health, Unit of Forensic Medicine, University of Verona , P.le L.A. Scuro 10, 37134 Verona, Italy.
  • Vanzetti L; Fondazione Bruno Kessler CMM-MNF , Via Sommarive 18, 38123 Trento, Italy.
  • Guella G; Department of Physics, University of Trento , Via Sommarive 14, 38123 Trento, Italy.
  • Bossi AM; Department of Biotechnology, University of Verona , Strada Le Grazie 15, 37134 Verona, Italy.
ACS Appl Mater Interfaces ; 9(8): 6908-6915, 2017 Mar 01.
Article in En | MEDLINE | ID: mdl-28151640
Molecular imprinted poly(acrylamido)-derivative nanogels have shown their selectivity to bind the protein human serum transferrin (HTR) and also showed their capability for instantaneous solvent-induced modification upon the addition of acetonitrile. Integrated to matrix-assisted laser desorption/ionization time-of-flight mass analysis the HTR-imprinted solvent-responsive nanogels permitted the determination of HTR straight from serum and offered novel perspectives in targeted protein analysis.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Limits: Humans Language: En Journal: ACS Appl Mater Interfaces Year: 2017 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Limits: Humans Language: En Journal: ACS Appl Mater Interfaces Year: 2017 Document type: Article