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Ester Prodrugs of IHVR-19029 with Enhanced Oral Exposure and Prevention of Gastrointestinal Glucosidase Interaction.
Ma, Julia; Wu, Shuo; Zhang, Xuexiang; Guo, Fang; Yang, Katherine; Guo, Jia; Su, Qing; Lu, Huagang; Lam, Patrick; Li, Yuhuan; Yan, Zhengyin; Kinney, William; Guo, Ju-Tao; Block, Timothy M; Chang, Jinhong; Du, Yanming.
Affiliation
  • Ma J; Baruch S. Blumberg Institute , 3805 Old Easton Road, Doylestown, Pennsylvania 18902, United States.
  • Wu S; Baruch S. Blumberg Institute , 3805 Old Easton Road, Doylestown, Pennsylvania 18902, United States.
  • Zhang X; Baruch S. Blumberg Institute , 3805 Old Easton Road, Doylestown, Pennsylvania 18902, United States.
  • Guo F; Baruch S. Blumberg Institute , 3805 Old Easton Road, Doylestown, Pennsylvania 18902, United States.
  • Yang K; University of Michigan , Ann Arbor, Michigan 48109, United States.
  • Guo J; Baruch S. Blumberg Institute , 3805 Old Easton Road, Doylestown, Pennsylvania 18902, United States.
  • Su Q; Baruch S. Blumberg Institute , 3805 Old Easton Road, Doylestown, Pennsylvania 18902, United States.
  • Lu H; Baruch S. Blumberg Institute , 3805 Old Easton Road, Doylestown, Pennsylvania 18902, United States.
  • Lam P; Lam Drug Discovery Consulting LLC , Chadds Ford, Pennsylvania 19317, United States.
  • Li Y; Institute of Medical Biotechnology, Chinese Academy of Medical Sciences , Beijing, China.
  • Yan Z; Genentech , South San Francisco, California 94080, United States.
  • Kinney W; Baruch S. Blumberg Institute , 3805 Old Easton Road, Doylestown, Pennsylvania 18902, United States.
  • Guo JT; Baruch S. Blumberg Institute , 3805 Old Easton Road, Doylestown, Pennsylvania 18902, United States.
  • Block TM; Baruch S. Blumberg Institute , 3805 Old Easton Road, Doylestown, Pennsylvania 18902, United States.
  • Chang J; Baruch S. Blumberg Institute , 3805 Old Easton Road, Doylestown, Pennsylvania 18902, United States.
  • Du Y; Baruch S. Blumberg Institute , 3805 Old Easton Road, Doylestown, Pennsylvania 18902, United States.
ACS Med Chem Lett ; 8(2): 157-162, 2017 Feb 09.
Article in En | MEDLINE | ID: mdl-28197304
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Full text: 1 Collection: 01-internacional Health context: 3_ND Database: MEDLINE Language: En Journal: ACS Med Chem Lett Year: 2017 Document type: Article
Fulltext
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XML
PubMed Links
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Full text: 1 Collection: 01-internacional Health context: 3_ND Database: MEDLINE Language: En Journal: ACS Med Chem Lett Year: 2017 Document type: Article