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Lafutidine, a histamine H2 receptor antagonist with mucosal protective properties, attenuates 5-fluorouracil-induced intestinal mucositis in mice through activation of extrinsic primary afferent neurons.
Sano, T; Utsumi, D; Amagase, K; Matsumoto, K; Tominaga, M; Higuchi, K; Takeuchi, T; Kato, S.
Affiliation
  • Sano T; Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto, Japan. beatatsuo0507@gmail.com.
  • Utsumi D; Second Department of Internal Medicine, Osaka Medical College, Takatsuki, Osaka, Japan.
  • Amagase K; Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto, Japan.
  • Matsumoto K; Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto, Japan.
  • Tominaga M; Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Yamashina, Kyoto, Japan.
  • Higuchi K; Division of Cell Signaling, Okazaki Institute for Integrative Bioscience, National Institutes of Natural Sciences, Okazaki, Aichi, Japan.
  • Takeuchi T; Second Department of Internal Medicine, Osaka Medical College, Takatsuki, Osaka, Japan.
  • Kato S; Second Department of Internal Medicine, Osaka Medical College, Takatsuki, Osaka, Japan.
J Physiol Pharmacol ; 68(1): 79-90, 2017 Feb.
Article in En | MEDLINE | ID: mdl-28456772
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Collection: 01-internacional Health context: 2_ODS3 Database: MEDLINE Main subject: Piperidines / Pyridines / Diarrhea / Mucositis / Histamine H2 Antagonists / Acetamides Limits: Animals Language: En Journal: J Physiol Pharmacol Year: 2017 Document type: Article
Search on Google
Print
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PubMed Links

Collection: 01-internacional Health context: 2_ODS3 Database: MEDLINE Main subject: Piperidines / Pyridines / Diarrhea / Mucositis / Histamine H2 Antagonists / Acetamides Limits: Animals Language: En Journal: J Physiol Pharmacol Year: 2017 Document type: Article