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Impact of cytosine methylation on DNA binding specificities of human transcription factors.
Yin, Yimeng; Morgunova, Ekaterina; Jolma, Arttu; Kaasinen, Eevi; Sahu, Biswajyoti; Khund-Sayeed, Syed; Das, Pratyush K; Kivioja, Teemu; Dave, Kashyap; Zhong, Fan; Nitta, Kazuhiro R; Taipale, Minna; Popov, Alexander; Ginno, Paul A; Domcke, Silvia; Yan, Jian; Schübeler, Dirk; Vinson, Charles; Taipale, Jussi.
Affiliation
  • Yin Y; Division of Functional Genomics and Systems Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE 141 83 Stockholm, Sweden.
  • Morgunova E; Division of Functional Genomics and Systems Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE 141 83 Stockholm, Sweden.
  • Jolma A; Division of Functional Genomics and Systems Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE 141 83 Stockholm, Sweden.
  • Kaasinen E; Division of Functional Genomics and Systems Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE 141 83 Stockholm, Sweden.
  • Sahu B; Genome-Scale Biology Program, Post Office Box 63, FI-00014 University of Helsinki, Helsinki, Finland.
  • Khund-Sayeed S; Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Room 3128, Building 37, Bethesda, MD 20892, USA.
  • Das PK; Genome-Scale Biology Program, Post Office Box 63, FI-00014 University of Helsinki, Helsinki, Finland.
  • Kivioja T; Genome-Scale Biology Program, Post Office Box 63, FI-00014 University of Helsinki, Helsinki, Finland.
  • Dave K; Division of Functional Genomics and Systems Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE 141 83 Stockholm, Sweden.
  • Zhong F; Division of Functional Genomics and Systems Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE 141 83 Stockholm, Sweden.
  • Nitta KR; Division of Functional Genomics and Systems Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE 141 83 Stockholm, Sweden.
  • Taipale M; Division of Functional Genomics and Systems Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE 141 83 Stockholm, Sweden.
  • Popov A; European Synchrotron Radiation Facility, 38043 Grenoble, France.
  • Ginno PA; Friedrich-Miescher-Institute for Biomedical Research (FMI), Maulbeerstrasse 66, 4058 Basel, Switzerland.
  • Domcke S; Friedrich-Miescher-Institute for Biomedical Research (FMI), Maulbeerstrasse 66, 4058 Basel, Switzerland.
  • Yan J; Faculty of Science, University of Basel, Petersplatz 1, 4003 Basel, Switzerland.
  • Schübeler D; Division of Functional Genomics and Systems Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE 141 83 Stockholm, Sweden.
  • Vinson C; Friedrich-Miescher-Institute for Biomedical Research (FMI), Maulbeerstrasse 66, 4058 Basel, Switzerland.
  • Taipale J; Faculty of Science, University of Basel, Petersplatz 1, 4003 Basel, Switzerland.
Science ; 356(6337)2017 05 05.
Article in En | MEDLINE | ID: mdl-28473536
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Dinucleoside Phosphates / DNA Methylation / Cytosine / Epigenesis, Genetic Limits: Humans Language: En Journal: Science Year: 2017 Document type: Article
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Dinucleoside Phosphates / DNA Methylation / Cytosine / Epigenesis, Genetic Limits: Humans Language: En Journal: Science Year: 2017 Document type: Article