VEGFA links self-renewal and metastasis by inducing Sox2 to repress miR-452, driving Slug.

Kim, M; Jang, K; Miller, P; Picon-Ruiz, M; Yeasky, T M; El-Ashry, D; Slingerland, J M

Kim, M; Jang, K; Miller, P; Picon-Ruiz, M; Yeasky, T M; El-Ashry, D; Slingerland, J M.

Affiliation

Kim M; Braman Family Breast Cancer Institute at Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Jang K; Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL, USA.
Miller P; Braman Family Breast Cancer Institute at Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Picon-Ruiz M; Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL, USA.
Yeasky TM; Braman Family Breast Cancer Institute at Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
El-Ashry D; Braman Family Breast Cancer Institute at Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Slingerland JM; Braman Family Breast Cancer Institute at Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.

Oncogene ; 36(36): 5199-5211, 2017 09 07.

Article in En | MEDLINE | ID: mdl-28504716

Subject(s)

Breast Neoplasms/pathology; Lung Neoplasms/secondary; MicroRNAs/genetics; Neoplastic Stem Cells/pathology; SOXB1 Transcription Factors/metabolism; Snail Family Transcription Factors/metabolism; Vascular Endothelial Growth Factor A/metabolism; Animals; Breast Neoplasms/genetics; Breast Neoplasms/metabolism; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms/genetics; Lung Neoplasms/metabolism; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells/metabolism; SOXB1 Transcription Factors/genetics; Snail Family Transcription Factors/genetics; Vascular Endothelial Growth Factor A/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / Breast Neoplasms / MicroRNAs / Vascular Endothelial Growth Factor A / SOXB1 Transcription Factors / Snail Family Transcription Factors / Lung Neoplasms Limits: Animals / Female / Humans Language: En Journal: Oncogene Year: 2017 Document type: Article

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