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Variants in the fetal genome near FLT1 are associated with risk of preeclampsia.
McGinnis, Ralph; Steinthorsdottir, Valgerdur; Williams, Nicholas O; Thorleifsson, Gudmar; Shooter, Scott; Hjartardottir, Sigrun; Bumpstead, Suzannah; Stefansdottir, Lilja; Hildyard, Lucy; Sigurdsson, Jon K; Kemp, John P; Silva, Gabriela B; Thomsen, Liv Cecilie V; Jääskeläinen, Tiina; Kajantie, Eero; Chappell, Sally; Kalsheker, Noor; Moffett, Ashley; Hiby, Susan; Lee, Wai Kwong; Padmanabhan, Sandosh; Simpson, Nigel A B; Dolby, Vivien A; Staines-Urias, Eleonora; Engel, Stephanie M; Haugan, Anita; Trogstad, Lill; Svyatova, Gulnara; Zakhidova, Nodira; Najmutdinova, Dilbar; Dominiczak, Anna F; Gjessing, Håkon K; Casas, Juan P; Dudbridge, Frank; Walker, James J; Pipkin, Fiona Broughton; Thorsteinsdottir, Unnur; Geirsson, Reynir T; Lawlor, Debbie A; Iversen, Ann-Charlotte; Magnus, Per; Laivuori, Hannele; Stefansson, Kari; Morgan, Linda.
Affiliation
  • McGinnis R; Wellcome Trust Sanger Institute, Cambridge, UK.
  • Steinthorsdottir V; deCODE Genetics/Amgen, Reykjavik, Iceland.
  • Williams NO; Wellcome Trust Sanger Institute, Cambridge, UK.
  • Thorleifsson G; deCODE Genetics/Amgen, Reykjavik, Iceland.
  • Shooter S; Wellcome Trust Sanger Institute, Cambridge, UK.
  • Hjartardottir S; Department of Obstetrics and Gynecology, Landspitali University Hospital, Reykjavik, Iceland.
  • Bumpstead S; Wellcome Trust Sanger Institute, Cambridge, UK.
  • Stefansdottir L; deCODE Genetics/Amgen, Reykjavik, Iceland.
  • Hildyard L; Wellcome Trust Sanger Institute, Cambridge, UK.
  • Sigurdsson JK; deCODE Genetics/Amgen, Reykjavik, Iceland.
  • Kemp JP; MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.
  • Silva GB; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia.
  • Thomsen LCV; Centre of Molecular Inflammation Research (CEMIR) and Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
  • Jääskeläinen T; St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
  • Kajantie E; Centre of Molecular Inflammation Research (CEMIR) and Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
  • Chappell S; Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway.
  • Kalsheker N; Medical and Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  • Moffett A; National Institute for Health and Welfare, Helsinki, Finland.
  • Hiby S; Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  • Lee WK; PEDEGO Research Unit, Oulu University Hospital and University of Oulu, Oulu, Finland.
  • Padmanabhan S; School of Life Sciences, University of Nottingham, Nottingham, UK.
  • Simpson NAB; School of Life Sciences, University of Nottingham, Nottingham, UK.
  • Dolby VA; Department of Pathology, University of Cambridge, Cambridge, UK.
  • Staines-Urias E; Department of Pathology, University of Cambridge, Cambridge, UK.
  • Engel SM; BHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
  • Haugan A; BHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
  • Trogstad L; Leeds Institute of Biomedical and Clinical Sciences, University of Leeds, Leeds, UK.
  • Svyatova G; Leeds Institute of Biomedical and Clinical Sciences, University of Leeds, Leeds, UK.
  • Zakhidova N; Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
  • Najmutdinova D; Nuffield Department of Obstetrics &Gynaecology, University of Oxford, Oxford, UK.
  • Dominiczak AF; Norwegian Institute of Public Health, Oslo, Norway.
  • Gjessing HK; Scientific Center of Obstetrics, Gynecology and Perinatology, Almaty, Kazakhstan.
  • Casas JP; Institute of Immunology, Uzbek Academy of Sciences, Tashkent, Uzbekistan.
  • Dudbridge F; Republic Specialized Scientific Practical Medical Centre of Obstetrics and Gynecology, Tashkent, Uzbekistan.
  • Thorsteinsdottir U; BHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
  • Geirsson RT; Norwegian Institute of Public Health, Oslo, Norway.
  • Lawlor DA; Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
  • Iversen AC; Farr Institute of Health Informatics, University College London, London, UK.
  • Magnus P; Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
  • Laivuori H; Leeds Institute of Biomedical and Clinical Sciences, University of Leeds, Leeds, UK.
  • Stefansson K; Medical School, University of Nottingham, Nottingham, UK.
  • Morgan L; deCODE Genetics/Amgen, Reykjavik, Iceland.
Nat Genet ; 49(8): 1255-1260, 2017 Aug.
Article in En | MEDLINE | ID: mdl-28628106
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Full text: 1 Collection: 01-internacional Health context: 2_ODS3 Database: MEDLINE Main subject: Pre-Eclampsia / Genetic Predisposition to Disease / Vascular Endothelial Growth Factor Receptor-1 / Fetus Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Female / Humans / Pregnancy Language: En Journal: Nat Genet Year: 2017 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Health context: 2_ODS3 Database: MEDLINE Main subject: Pre-Eclampsia / Genetic Predisposition to Disease / Vascular Endothelial Growth Factor Receptor-1 / Fetus Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Female / Humans / Pregnancy Language: En Journal: Nat Genet Year: 2017 Document type: Article