A prospective examination of circulating tumor cell profiles in non-small-cell lung cancer molecular subgroups.

Lindsay, C R; Faugeroux, V; Michiels, S; Pailler, E; Facchinetti, F; Ou, D; Bluthgen, M V; Pannet, C; Ngo-Camus, M; Bescher, G; Caramella, C; Billiot, F; Remon, J; Planchard, D; Soria, J-C; Besse, B; Farace, F

Lindsay, C R; Faugeroux, V; Michiels, S; Pailler, E; Facchinetti, F; Ou, D; Bluthgen, M V; Pannet, C; Ngo-Camus, M; Bescher, G; Caramella, C; Billiot, F; Remon, J; Planchard, D; Soria, J-C; Besse, B; Farace, F.

Affiliation

Lindsay CR; INSERM U981, University of Paris-Sud XI, Translational Research Laboratory, Gustave Roussy Cancer Campus, Villejuif, France.
Faugeroux V; INSERM U981, University of Paris-Sud XI, Translational Research Laboratory, Gustave Roussy Cancer Campus, Villejuif, France.
Michiels S; Department of Biostatistics and Epidemiology, Gustave Roussy Cancer Campus, Villejuif, France.
Pailler E; INSERM U981, University of Paris-Sud XI, Translational Research Laboratory, Gustave Roussy Cancer Campus, Villejuif, France.
Facchinetti F; INSERM U981, University of Paris-Sud XI, Translational Research Laboratory, Gustave Roussy Cancer Campus, Villejuif, France.
Ou D; Department of Cancer Medicine, Gustave Roussy Cancer Campus, Villejuif, France.
Bluthgen MV; Department of Cancer Medicine, Gustave Roussy Cancer Campus, Villejuif, France.
Pannet C; Department of Cancer Medicine, Gustave Roussy Cancer Campus, Villejuif, France.
Ngo-Camus M; Drug Development Department, Gustave Roussy Cancer Campus, Villejuif, France.
Bescher G; Department of Cancer Medicine, Gustave Roussy Cancer Campus, Villejuif, France.
Caramella C; Department of Radiology, Gustave Roussy Cancer Campus, Villejuif, France.
Billiot F; INSERM U981, University of Paris-Sud XI, Translational Research Laboratory, Gustave Roussy Cancer Campus, Villejuif, France.
Remon J; Department of Cancer Medicine, Gustave Roussy Cancer Campus, Villejuif, France.
Planchard D; Department of Cancer Medicine, Gustave Roussy Cancer Campus, Villejuif, France.
Soria JC; INSERM U981, University of Paris-Sud XI, Translational Research Laboratory, Gustave Roussy Cancer Campus, Villejuif, France.
Besse B; Drug Development Department, Gustave Roussy Cancer Campus, Villejuif, France.
Farace F; INSERM U981, University of Paris-Sud XI, Translational Research Laboratory, Gustave Roussy Cancer Campus, Villejuif, France.

Ann Oncol ; 28(7): 1523-1531, 2017 Jul 01.

Article in En | MEDLINE | ID: mdl-28633480

Subject(s)

Biomarkers, Tumor/blood; Carcinoma, Non-Small-Cell Lung/blood; Lung Neoplasms/blood; Neoplastic Cells, Circulating/metabolism; Adult; Aged; Aged, 80 and over; Anaplastic Lymphoma Kinase; Biomarkers, Tumor/genetics; Carcinoma, Non-Small-Cell Lung/genetics; Carcinoma, Non-Small-Cell Lung/mortality; Carcinoma, Non-Small-Cell Lung/pathology; Disease-Free Survival; Epithelial-Mesenchymal Transition; ErbB Receptors/genetics; Female; Gene Rearrangement; Genotype; Humans; Immunomagnetic Separation; Kaplan-Meier Estimate; Lung Neoplasms/genetics; Lung Neoplasms/mortality; Lung Neoplasms/pathology; Male; Middle Aged; Multivariate Analysis; Mutation; Neoplasm Staging; Neoplastic Cells, Circulating/pathology; Phenotype; Proportional Hazards Models; Prospective Studies; Proto-Oncogene Proteins p21(ras)/genetics; Receptor Protein-Tyrosine Kinases/genetics; Time Factors; Vimentin/blood

Key words

CTC; EMT; biomarker; circulating tumor cell; non-small-cell lung cancer; vimentin

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Full text: 1 Collection: 01-internacional Health context: 6_ODS3_enfermedades_notrasmisibles Database: MEDLINE Main subject: Biomarkers, Tumor / Carcinoma, Non-Small-Cell Lung / Lung Neoplasms / Neoplastic Cells, Circulating Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged80 Language: En Journal: Ann Oncol Year: 2017 Document type: Article

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