Resistance of mice to Leptospira infection and correlation with chemokine response.

Domingos, R H; Pavanel, E B; Nakajima, E; Schons-Fonseca, L; Da Costa, R M A; De Franco, M; Carvalho, E; Ho, P L; Martins, E A; Da Silva, J B

Domingos, R H; Pavanel, E B; Nakajima, E; Schons-Fonseca, L; Da Costa, R M A; De Franco, M; Carvalho, E; Ho, P L; Martins, E A; Da Silva, J B.

Affiliation

Domingos RH; Centro de Biotecnologia, Instituto Butantan, São Paulo, 05503-900, Brazil.
Pavanel EB; Centro de Biotecnologia, Instituto Butantan, São Paulo, 05503-900, Brazil.
Nakajima E; Centro de Biotecnologia, Instituto Butantan, São Paulo, 05503-900, Brazil.
Schons-Fonseca L; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Da Costa RMA; Global Antibiotics Research and Development Partnership (GARDP), Drugs for Neglected Diseases initiative (DNDi), Chemin Louis-Dunant 15, 1202 Geneva, Switzerland.
De Franco M; Laboratório de Imunogenética, Instituto Butantan, São Paulo, 05503-900, Brazil.
Carvalho E; Centro de Biotecnologia, Instituto Butantan, São Paulo, 05503-900, Brazil.
Ho PL; Laboratório Especial de Inovação e Desenvolvimento Industrial, Instituto Butantan, São Paulo, 05503-900, Brazil.
Martins EA; Centro de Biotecnologia, Instituto Butantan, São Paulo, 05503-900, Brazil.
Da Silva JB; Centro de Biotecnologia, Instituto Butantan, São Paulo, 05503-900, Brazil. Electronic address: josefa.silva@butantan.gov.br.

Immunobiology ; 222(11): 1004-1013, 2017 11.

Article in En | MEDLINE | ID: mdl-28641918

Subject(s)

Chemokines/metabolism; Leptospira/immunology; Leptospirosis/pathology; Lung/physiology; Animals; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Cells, Cultured; Disease Progression; Gene Expression Regulation, Bacterial; Hemolysin Proteins/genetics; Hemolysin Proteins/metabolism; Host-Pathogen Interactions; Immunity, Innate; Inflammation Mediators/metabolism; Leptospirosis/immunology; Lung/microbiology; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Microfilament Proteins/genetics; Microfilament Proteins/metabolism; Toll-Like Receptor 4/metabolism

Key words

C3H/HeJ mice; Chemokines; Leptospira infection; Pathogen-host interaction

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Full text: 1 Collection: 01-internacional Health context: 2_ODS3 Database: MEDLINE Main subject: Chemokines / Leptospira / Leptospirosis / Lung Limits: Animals Language: En Journal: Immunobiology Year: 2017 Document type: Article

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