Mechanisms of bone destruction in multiple myeloma.

Terpos, E; Christoulas, D; Gavriatopoulou, M; Dimopoulos, M A

Terpos, E; Christoulas, D; Gavriatopoulou, M; Dimopoulos, M A.

Affiliation

Terpos E; Department of Clinical Therapeutics, National and Kapodistrian University of Athens School of Medicine, Alexandra General Hospital, Athens, Greece.
Christoulas D; Department of Clinical Therapeutics, National and Kapodistrian University of Athens School of Medicine, Alexandra General Hospital, Athens, Greece.
Gavriatopoulou M; Department of Clinical Therapeutics, National and Kapodistrian University of Athens School of Medicine, Alexandra General Hospital, Athens, Greece.
Dimopoulos MA; Department of Clinical Therapeutics, National and Kapodistrian University of Athens School of Medicine, Alexandra General Hospital, Athens, Greece.

Eur J Cancer Care (Engl) ; 26(6)2017 Nov.

Article in En | MEDLINE | ID: mdl-28940410

Subject(s)

Bone Resorption/physiopathology; Multiple Myeloma/physiopathology; Osteolysis/physiopathology; Adaptor Proteins, Signal Transducing; Apoptosis; Bone Morphogenetic Proteins/metabolism; Bone Resorption/etiology; Genetic Markers; Humans; Intercellular Signaling Peptides and Proteins/metabolism; Multiple Myeloma/complications; Multiple Myeloma/metabolism; Osteoclasts/physiology; Osteocytes/physiology; Osteogenesis/physiology; Osteolysis/etiology; Osteolysis/metabolism; Osteoprotegerin/metabolism; RANK Ligand/metabolism; Wnt Signaling Pathway

Key words

Wnt pathway; bone disease; chemokine (C-C motif) ligand 3; growth factor independence-1; multiple myeloma; osteocyte; receptor activator of nuclear factor-kB ligand (RANKL)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteolysis / Bone Resorption / Multiple Myeloma Type of study: Etiology_studies Limits: Humans Language: En Journal: Eur J Cancer Care (Engl) Year: 2017 Document type: Article

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