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Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani.
Torrie, Leah S; Brand, Stephen; Robinson, David A; Ko, Eun Jung; Stojanovski, Laste; Simeons, Frederick R C; Wyllie, Susan; Thomas, John; Ellis, Lucy; Osuna-Cabello, Maria; Epemolu, Ola; Nühs, Andrea; Riley, Jennifer; MacLean, Lorna; Manthri, Sujatha; Read, Kevin D; Gilbert, Ian H; Fairlamb, Alan H; De Rycker, Manu.
Affiliation
  • Torrie LS; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee , Dow Street, Dundee DD1 5EH, United Kingdom.
  • Brand S; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee , Dow Street, Dundee DD1 5EH, United Kingdom.
  • Robinson DA; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee , Dow Street, Dundee DD1 5EH, United Kingdom.
  • Ko EJ; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee , Dow Street, Dundee DD1 5EH, United Kingdom.
  • Stojanovski L; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee , Dow Street, Dundee DD1 5EH, United Kingdom.
  • Simeons FRC; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee , Dow Street, Dundee DD1 5EH, United Kingdom.
  • Wyllie S; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee , Dow Street, Dundee DD1 5EH, United Kingdom.
  • Thomas J; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee , Dow Street, Dundee DD1 5EH, United Kingdom.
  • Ellis L; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee , Dow Street, Dundee DD1 5EH, United Kingdom.
  • Osuna-Cabello M; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee , Dow Street, Dundee DD1 5EH, United Kingdom.
  • Epemolu O; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee , Dow Street, Dundee DD1 5EH, United Kingdom.
  • Nühs A; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee , Dow Street, Dundee DD1 5EH, United Kingdom.
  • Riley J; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee , Dow Street, Dundee DD1 5EH, United Kingdom.
  • MacLean L; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee , Dow Street, Dundee DD1 5EH, United Kingdom.
  • Manthri S; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee , Dow Street, Dundee DD1 5EH, United Kingdom.
  • Read KD; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee , Dow Street, Dundee DD1 5EH, United Kingdom.
  • Gilbert IH; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee , Dow Street, Dundee DD1 5EH, United Kingdom.
  • Fairlamb AH; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee , Dow Street, Dundee DD1 5EH, United Kingdom.
  • De Rycker M; Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee , Dow Street, Dundee DD1 5EH, United Kingdom.
ACS Infect Dis ; 3(10): 718-727, 2017 10 13.
Article in En | MEDLINE | ID: mdl-28967262
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leishmania donovani / Enzyme Inhibitors / Methionine-tRNA Ligase / Antiprotozoal Agents Language: En Journal: ACS Infect Dis Year: 2017 Document type: Article
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leishmania donovani / Enzyme Inhibitors / Methionine-tRNA Ligase / Antiprotozoal Agents Language: En Journal: ACS Infect Dis Year: 2017 Document type: Article