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The deubiquitinase UCHL5/UCH37 positively regulates Hedgehog signaling by deubiquitinating Smoothened.
Zhou, Zizhang; Yao, Xia; Pang, Shu; Chen, Ping; Jiang, Weirong; Shan, Zhaoliang; Zhang, Qing.
Affiliation
  • Zhou Z; State Key Laboratory of Pharmaceutical Biotechnology and MOE Key Laboratory of Model Animals for Disease Study, Model Animal Research Center of Nanjing University, Nanjing, China.
  • Yao X; Collaborative Innovation Center of Genetics and Development, Shanghai, China.
  • Pang S; State Key Laboratory of Pharmaceutical Biotechnology and MOE Key Laboratory of Model Animals for Disease Study, Model Animal Research Center of Nanjing University, Nanjing, China.
  • Chen P; Collaborative Innovation Center of Genetics and Development, Shanghai, China.
  • Jiang W; State Key Laboratory of Pharmaceutical Biotechnology and MOE Key Laboratory of Model Animals for Disease Study, Model Animal Research Center of Nanjing University, Nanjing, China.
  • Shan Z; Collaborative Innovation Center of Genetics and Development, Shanghai, China.
  • Zhang Q; State Key Laboratory of Pharmaceutical Biotechnology and MOE Key Laboratory of Model Animals for Disease Study, Model Animal Research Center of Nanjing University, Nanjing, China.
J Mol Cell Biol ; 10(3): 243-257, 2018 06 01.
Article in En | MEDLINE | ID: mdl-28992318
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Drosophila Proteins / Ubiquitin Thiolesterase / Drosophila / Hedgehog Proteins / Smoothened Receptor Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Mol Cell Biol Year: 2018 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Drosophila Proteins / Ubiquitin Thiolesterase / Drosophila / Hedgehog Proteins / Smoothened Receptor Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Mol Cell Biol Year: 2018 Document type: Article