Incidence of pertussis in subjects aged 50years and older in France in 2013-2014.
Med Mal Infect
; 48(1): 30-36, 2018 Feb.
Article
in En
| MEDLINE
| ID: mdl-29037454
ABSTRACT
OBJECTIVE:
To assess the incidence of pertussis (whooping cough) in subjects aged 50years and older in France.METHODS:
Participating family physicians (FPs) using the patient record management software AxiSanté® included patients aged 50years and older, who had signed an informed consent form, presenting with persistent cough for 7 to 21days. Bordetella genetic material was detected by polymerase chain reaction (PCR) on nasopharyngeal samples collected at the FP's discretion.RESULTS:
A total of 42 FPs included 129 patients from June 2013 to August 2014 (large cities 38; medium-sized cities 57; rural areas 34); 106 samples were analyzed. Overall, 30 pertussis cases were diagnosed 10 cases confirmed by PCR, 18 purely clinical cases, and two direct epidemiological cases. The crude incidence rate per 100,000 patients aged≥50years was 103.6 (95% CI 69.9-47.9) 77.1 in large cities, 103.1 in medium-sized cities, and 143.9 in rural areas. The extrapolated incidence rate per 100,000 persons aged≥50years was 187.1 (95% CI 126.2-67.1) 131.1 in large cities, 256.1 in medium-sized cities, and 242.2 in rural areas.CONCLUSION:
The population aged 50years and older can serve as a reservoir. Its role in Bordetella pertussis circulation should be taken into account for pertussis booster vaccination programs.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Whooping Cough
Type of study:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Europa
Language:
En
Journal:
Med Mal Infect
Year:
2018
Document type:
Article