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Nonlatching positive feedback enables robust bimodality by decoupling expression noise from the mean.
Razooky, Brandon S; Cao, Youfang; Hansen, Maike M K; Perelson, Alan S; Simpson, Michael L; Weinberger, Leor S.
Affiliation
  • Razooky BS; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York, United States of America.
  • Cao Y; The Gladstone Institutes (Virology and Immunology), San Francisco, California, United States of America.
  • Hansen MMK; Biophysics Graduate Group, University of California, San Francisco, San Francisco, California, United Sates of America.
  • Perelson AS; Center for Nanophase Materials Sciences, Oak Ridge National Laboratory, Oak Ridge, Tennessee, United States of America.
  • Simpson ML; Bredesen Center for Interdisciplinary Research and Graduate Education, University of Tennessee, Knoxville, Tennessee, United States of America.
  • Weinberger LS; Theoretical Biology and Biophysics (T-6), Los Alamos National Laboratory, Los Alamos, New Mexico, United States of America.
PLoS Biol ; 15(10): e2000841, 2017 Oct.
Article in En | MEDLINE | ID: mdl-29045398
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Full text: 1 Collection: 01-internacional Health context: 2_ODS3 Database: MEDLINE Main subject: Gene Expression Regulation, Viral / HIV-1 / Feedback, Physiological / Tat Gene Products, Human Immunodeficiency Virus Type of study: Prognostic_studies Limits: Humans Language: En Journal: PLoS Biol Year: 2017 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Health context: 2_ODS3 Database: MEDLINE Main subject: Gene Expression Regulation, Viral / HIV-1 / Feedback, Physiological / Tat Gene Products, Human Immunodeficiency Virus Type of study: Prognostic_studies Limits: Humans Language: En Journal: PLoS Biol Year: 2017 Document type: Article