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Sophocarpine attenuates wear particle-induced implant loosening by inhibiting osteoclastogenesis and bone resorption via suppression of the NF-κB signalling pathway in a rat model.
Zhou, Chen-He; Shi, Zhong-Li; Meng, Jia-Hong; Hu, Bin; Zhao, Chen-Chen; Yang, Yu-Te; Yu, Wei; Chen, Ze-Xin; Heng, Boon Chin; Parkman, Virginia-Jeni Akila; Jiang, Shuai; Zhu, Han-Xiao; Wu, Hao-Bo; Shen, Wei-Liang; Yan, Shi-Gui.
Affiliation
  • Zhou CH; Department of Orthopedic Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
  • Shi ZL; Orthopedic Research Institute of Zhejiang University, Hangzhou, China.
  • Meng JH; Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA, USA.
  • Hu B; Department of Orthopedic Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
  • Zhao CC; Orthopedic Research Institute of Zhejiang University, Hangzhou, China.
  • Yang YT; Department of Orthopedic Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
  • Yu W; Orthopedic Research Institute of Zhejiang University, Hangzhou, China.
  • Chen ZX; Department of Orthopedic Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
  • Heng BC; Orthopedic Research Institute of Zhejiang University, Hangzhou, China.
  • Parkman VA; Department of Orthopedic Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
  • Jiang S; Orthopedic Research Institute of Zhejiang University, Hangzhou, China.
  • Zhu HX; Department of Orthopedic Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
  • Wu HB; Orthopedic Research Institute of Zhejiang University, Hangzhou, China.
  • Shen WL; Department of Orthopedic Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
  • Yan SG; Orthopedic Research Institute of Zhejiang University, Hangzhou, China.
Br J Pharmacol ; 175(6): 859-876, 2018 03.
Article in En | MEDLINE | ID: mdl-29130485
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoclasts / Osteogenesis / Bone Resorption / Alkaloids Type of study: Prognostic_studies Limits: Animals Language: En Journal: Br J Pharmacol Year: 2018 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoclasts / Osteogenesis / Bone Resorption / Alkaloids Type of study: Prognostic_studies Limits: Animals Language: En Journal: Br J Pharmacol Year: 2018 Document type: Article