Amustaline (S-303) treatment inactivates high levels of Chikungunya virus in red-blood-cell components.

Aubry, M; Laughhunn, A; Santa Maria, F; Lanteri, M C; Stassinopoulos, A; Musso, D

Aubry, M; Laughhunn, A; Santa Maria, F; Lanteri, M C; Stassinopoulos, A; Musso, D.

Affiliation

Aubry M; Pôle de recherche et de veille sur les maladies infectieuses émergentes, Institut Louis Malardé, Tahiti, French Polynesia.
Laughhunn A; Aix Marseille Univ, IRD (Dakar, Marseille, Papeete), AP-HM, IHU-Méditerranée Infection, UMR Vecteurs - Infections Tropicales et Méditerranéennes (VITROME), Marseille, France.
Santa Maria F; Cerus Corporation, Concord, CA, USA.
Lanteri MC; Cerus Corporation, Concord, CA, USA.
Stassinopoulos A; Cerus Corporation, Concord, CA, USA.
Musso D; Cerus Corporation, Concord, CA, USA.

Vox Sang ; 113(3): 232-241, 2018 Apr.

Article in En | MEDLINE | ID: mdl-29314033

Subject(s)

Acridines/therapeutic use; Antiviral Agents/therapeutic use; Blood Safety/methods; Chikungunya Fever/prevention & control; Nitrogen Mustard Compounds/therapeutic use; Virus Inactivation; Acridines/pharmacology; Antiviral Agents/pharmacology; Chikungunya Fever/blood; Chikungunya virus/drug effects; Erythrocytes/virology; Humans; Nitrogen Mustard Compounds/pharmacology; Viral Load

Key words

NAT testing; Transfusion-transmissible infections; pathogen inactivation; red cell components

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Health context: 2_ODS3 / 3_ND Database: MEDLINE Main subject: Antiviral Agents / Acridines / Virus Inactivation / Blood Safety / Chikungunya Fever / Nitrogen Mustard Compounds Limits: Humans Language: En Journal: Vox Sang Year: 2018 Document type: Article

Fulltext

XML

PubMed Links

Search on Google