Toxicity and efficacy of lomustine and bevacizumab in recurrent glioblastoma patients.

Jakobsen, J N; Urup, T; Grunnet, K; Toft, A; Johansen, M D; Poulsen, S H; Christensen, I J; Muhic, A; Poulsen, H S

Jakobsen, J N; Urup, T; Grunnet, K; Toft, A; Johansen, M D; Poulsen, S H; Christensen, I J; Muhic, A; Poulsen, H S.

Affiliation

Jakobsen JN; Department of Oncology, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark. jan.nyrop.jakobsen@regionh.dk.
Urup T; Department of Oncology, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Grunnet K; Department of Radiation Biology, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Toft A; Department of Radiation Biology, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Johansen MD; Department of Radiation Biology, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Poulsen SH; Department of Oncology, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Christensen IJ; Department of Radiation Biology, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Muhic A; Department of Surgical Gastroenterology, Hvidovre Hospital, Kettegårds Alle 30, Hvidovre, Denmark.
Poulsen HS; Department of Oncology, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.

J Neurooncol ; 137(2): 439-446, 2018 Apr.

Article in En | MEDLINE | ID: mdl-29330749

Subject(s)

Antineoplastic Agents, Immunological/therapeutic use; Bevacizumab/therapeutic use; Brain Neoplasms/drug therapy; Glioblastoma/drug therapy; Lomustine/therapeutic use; Adult; Aged; Antineoplastic Agents, Immunological/toxicity; Antineoplastic Combined Chemotherapy Protocols/toxicity; Bevacizumab/toxicity; Brain Neoplasms/mortality; Female; Follow-Up Studies; Glioblastoma/mortality; Humans; Irinotecan/therapeutic use; Irinotecan/toxicity; Lomustine/toxicity; Male; Middle Aged; Neoplasm Recurrence, Local/drug therapy; Neoplasm Recurrence, Local/metabolism; Salvage Therapy; Treatment Outcome; Young Adult

Key words

Bevacizumab; Chemotherapy; Glioblastoma; Irinotecan; Lonustine; Recurrent glioblastoma

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Full text: 1 Collection: 01-internacional Health context: 3_ND Database: MEDLINE Main subject: Brain Neoplasms / Glioblastoma / Bevacizumab / Antineoplastic Agents, Immunological / Lomustine Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: J Neurooncol Year: 2018 Document type: Article

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