Pharmacokinetics and Safety of Intravenous Murepavadin Infusion in Healthy Adult Subjects Administered Single and Multiple Ascending Doses.

Wach, Achim; Dembowsky, Klaus; Dale, Glenn E

Wach, Achim; Dembowsky, Klaus; Dale, Glenn E.

Affiliation

Wach A; Polyphor Ltd., Allschwil, Switzerland.
Dembowsky K; Polyphor Ltd., Allschwil, Switzerland.
Dale GE; Polyphor Ltd., Allschwil, Switzerland glenn.dale@polyphor.com.

Antimicrob Agents Chemother ; 62(4)2018 04.

Article in En | MEDLINE | ID: mdl-29437621

Subject(s)

Anti-Bacterial Agents/adverse effects; Anti-Bacterial Agents/pharmacokinetics; Peptides, Cyclic/adverse effects; Peptides, Cyclic/pharmacokinetics; Adult; Anti-Bacterial Agents/administration & dosage; Dose-Response Relationship, Drug; Double-Blind Method; Healthy Volunteers; Humans; Infusions, Intravenous; Male; Peptides, Cyclic/administration & dosage; Young Adult

Key words

murepavadin; pharmacokinetics; phase 1 study

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides, Cyclic / Anti-Bacterial Agents Type of study: Clinical_trials Limits: Adult / Humans / Male Language: En Journal: Antimicrob Agents Chemother Year: 2018 Document type: Article

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