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Development of (6 R)-2-Nitro-6-[4-(trifluoromethoxy)phenoxy]-6,7-dihydro-5 H-imidazo[2,1- b][1,3]oxazine (DNDI-8219): A New Lead for Visceral Leishmaniasis.
Thompson, Andrew M; O'Connor, Patrick D; Marshall, Andrew J; Blaser, Adrian; Yardley, Vanessa; Maes, Louis; Gupta, Suman; Launay, Delphine; Braillard, Stephanie; Chatelain, Eric; Wan, Baojie; Franzblau, Scott G; Ma, Zhenkun; Cooper, Christopher B; Denny, William A.
Affiliation
  • Thompson AM; Auckland Cancer Society Research Centre, School of Medical Sciences , The University of Auckland , Private Bag 92019, Auckland 1142 , New Zealand.
  • O'Connor PD; Auckland Cancer Society Research Centre, School of Medical Sciences , The University of Auckland , Private Bag 92019, Auckland 1142 , New Zealand.
  • Marshall AJ; Auckland Cancer Society Research Centre, School of Medical Sciences , The University of Auckland , Private Bag 92019, Auckland 1142 , New Zealand.
  • Blaser A; Auckland Cancer Society Research Centre, School of Medical Sciences , The University of Auckland , Private Bag 92019, Auckland 1142 , New Zealand.
  • Yardley V; Faculty of Infectious & Tropical Diseases , London School of Hygiene & Tropical Medicine , Keppel Street , London WC1E 7HT , United Kingdom.
  • Maes L; Laboratory for Microbiology, Parasitology and Hygiene, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences , University of Antwerp , Universiteitsplein 1 , B-2610 Antwerp , Belgium.
  • Gupta S; Division of Parasitology , CSIR-Central Drug Research Institute , Lucknow 226031 , India.
  • Launay D; Drugs for Neglected Diseases initiative, 15 Chemin Louis Dunant , 1202 Geneva , Switzerland.
  • Braillard S; Drugs for Neglected Diseases initiative, 15 Chemin Louis Dunant , 1202 Geneva , Switzerland.
  • Chatelain E; Drugs for Neglected Diseases initiative, 15 Chemin Louis Dunant , 1202 Geneva , Switzerland.
  • Wan B; Institute for Tuberculosis Research, College of Pharmacy , University of Illinois at Chicago , 833 South Wood Street , Chicago , Illinois 60612 , United States.
  • Franzblau SG; Institute for Tuberculosis Research, College of Pharmacy , University of Illinois at Chicago , 833 South Wood Street , Chicago , Illinois 60612 , United States.
  • Ma Z; Global Alliance for TB Drug Development , 40 Wall Street , New York , New York 10005 , United States.
  • Cooper CB; Global Alliance for TB Drug Development , 40 Wall Street , New York , New York 10005 , United States.
  • Denny WA; Auckland Cancer Society Research Centre, School of Medical Sciences , The University of Auckland , Private Bag 92019, Auckland 1142 , New Zealand.
J Med Chem ; 61(6): 2329-2352, 2018 03 22.
Article in En | MEDLINE | ID: mdl-29461823
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Full text: 1 Collection: 01-internacional Health context: 3_ND Database: MEDLINE Main subject: Oxazines / Leishmaniasis, Visceral / Antiparasitic Agents Limits: Animals Language: En Journal: J Med Chem Year: 2018 Document type: Article
Fulltext
Print
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PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Health context: 3_ND Database: MEDLINE Main subject: Oxazines / Leishmaniasis, Visceral / Antiparasitic Agents Limits: Animals Language: En Journal: J Med Chem Year: 2018 Document type: Article