Optic nerve regeneration in the mouse is a complex trait modulated by genetic background.

Wang, Jiaxing; Li, Ying; King, Rebecca; Struebing, Felix L; Geisert, Eldon E

Wang, Jiaxing; Li, Ying; King, Rebecca; Struebing, Felix L; Geisert, Eldon E.

Affiliation

Wang J; Department of Ophthalmology, Tianjin Medical University General Hospital, Tianjin, China.
Li Y; Department of Ophthalmology, Emory University, Atlanta, GA.
King R; Department of Ophthalmology, Emory University, Atlanta, GA.
Struebing FL; Department of Ophthalmology, Emory University, Atlanta, GA.
Geisert EE; Department of Ophthalmology, Emory University, Atlanta, GA.

Mol Vis ; 24: 174-186, 2018.

Article in En | MEDLINE | ID: mdl-29463955

Subject(s)

Axons/metabolism; Genetic Background; Nerve Regeneration/genetics; Optic Nerve/metabolism; PTEN Phosphohydrolase/genetics; Animals; Axons/ultrastructure; Cholera Toxin/chemistry; Crosses, Genetic; Cyclic AMP/administration & dosage; Cyclic AMP/analogs & derivatives; Dependovirus/genetics; Dependovirus/metabolism; Gene Expression Profiling; Gene Expression Regulation; Gene Knockdown Techniques; Genetic Vectors/chemistry; Genetic Vectors/metabolism; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nerve Crush/methods; Optic Nerve/pathology; PTEN Phosphohydrolase/metabolism; Retinal Ganglion Cells/cytology; Retinal Ganglion Cells/metabolism; Thionucleotides/administration & dosage; Zymosan/administration & dosage

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Optic Nerve / Axons / PTEN Phosphohydrolase / Genetic Background / Nerve Regeneration Limits: Animals Language: En Journal: Mol Vis Year: 2018 Document type: Article

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