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The presence of glutamate residues on the PAS sequence of the stimuli-sensitive nano-ferritin improves in vivo biodistribution and mitoxantrone encapsulation homogeneity.
Falvo, Elisabetta; Malagrinò, Francesca; Arcovito, Alessandro; Fazi, Francesco; Colotti, Gianni; Tremante, Elisa; Di Micco, Patrizio; Braca, Aldo; Opri, Roberta; Giuffrè, Alessandro; Fracasso, Giulio; Ceci, Pierpaolo.
Affiliation
  • Falvo E; Institute of Molecular Biology and Pathology, CNR - National Research Council of Italy, 00185 Rome, Italy.
  • Malagrinò F; Institute of Molecular Biology and Pathology, CNR - National Research Council of Italy, 00185 Rome, Italy; Department of Biochemical Sciences "A. Rossi-Fanelli", "Sapienza" University, 00185 Rome, Italy.
  • Arcovito A; Institute of Biochemistry and Clinical Biochemistry, Catholic University of Sacred Heart, 00168 Rome, Italy.
  • Fazi F; Department of Anatomical, Histological, Forensic & Orthopedic Sciences, Section of Histology & Medical Embryology, "Sapienza" University, 00161 Rome, Italy.
  • Colotti G; Institute of Molecular Biology and Pathology, CNR - National Research Council of Italy, 00185 Rome, Italy.
  • Tremante E; Oncogenomics and Epigenetics, Regina Elena National Cancer Institute, 00144 Rome, Italy.
  • Di Micco P; Department of Biochemical Sciences "A. Rossi-Fanelli", "Sapienza" University, 00185 Rome, Italy.
  • Braca A; BSP Pharmaceuticals, 04013 Latina, Italy.
  • Opri R; Department of Medicine, University of Verona, 37134 Verona, Italy.
  • Giuffrè A; Institute of Molecular Biology and Pathology, CNR - National Research Council of Italy, 00185 Rome, Italy.
  • Fracasso G; Department of Medicine, University of Verona, 37134 Verona, Italy. Electronic address: giulio.fracasso@univr.it.
  • Ceci P; Institute of Molecular Biology and Pathology, CNR - National Research Council of Italy, 00185 Rome, Italy. Electronic address: pierpaolo.ceci@cnr.it.
J Control Release ; 275: 177-185, 2018 04 10.
Article in En | MEDLINE | ID: mdl-29474961
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apoferritins / Drug Carriers / Doxorubicin / Mitoxantrone / Glutamic Acid / Nanoparticles / Antineoplastic Agents Type of study: Diagnostic_studies Limits: Humans Language: En Journal: J Control Release Year: 2018 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apoferritins / Drug Carriers / Doxorubicin / Mitoxantrone / Glutamic Acid / Nanoparticles / Antineoplastic Agents Type of study: Diagnostic_studies Limits: Humans Language: En Journal: J Control Release Year: 2018 Document type: Article