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Previously reported placebo-response-associated variants do not predict patient outcomes in inflammatory disease Phase III trial placebo arms.
Haug-Baltzell, Asher; Bhangale, Tushar R; Chang, Diana; Dressen, Amy; Yaspan, Brian L; Ortmann, Ward; Brauer, Matthew J; Hunkapiller, Julie; Reeder, Jens; Mukhyala, Kiran; Cuenco, Karen T; Tom, Jennifer A; Cowgill, Amy; Vogel, Jan; Forrest, William F; Behrens, Timothy W; Graham, Robert R; Wuster, Arthur.
Affiliation
  • Haug-Baltzell A; Genetics Interdisciplinary Group, University of Arizona, Tucson, AZ, 85719, USA.
  • Bhangale TR; Department of Human Genetics, Genentech Inc, South San Francisco, 94080, CA, USA.
  • Chang D; Department of Human Genetics, Genentech Inc, South San Francisco, 94080, CA, USA.
  • Dressen A; Department of Bioinformatics and Computational Biology, Genentech Inc, South San Francisco, 94080, CA, USA.
  • Yaspan BL; Department of Human Genetics, Genentech Inc, South San Francisco, 94080, CA, USA.
  • Ortmann W; Department of Human Genetics, Genentech Inc, South San Francisco, 94080, CA, USA.
  • Brauer MJ; Department of Human Genetics, Genentech Inc, South San Francisco, 94080, CA, USA.
  • Hunkapiller J; Biosample and Depository Management, Genentech Inc, South San Francisco, CA, 94080, USA.
  • Reeder J; Department of Bioinformatics and Computational Biology, Genentech Inc, South San Francisco, 94080, CA, USA.
  • Mukhyala K; Department of Human Genetics, Genentech Inc, South San Francisco, 94080, CA, USA.
  • Cuenco KT; Department of Bioinformatics and Computational Biology, Genentech Inc, South San Francisco, 94080, CA, USA.
  • Tom JA; Department of Bioinformatics and Computational Biology, Genentech Inc, South San Francisco, 94080, CA, USA.
  • Cowgill A; Department of Human Genetics, Genentech Inc, South San Francisco, 94080, CA, USA.
  • Vogel J; Department of Bioinformatics and Computational Biology, Genentech Inc, South San Francisco, 94080, CA, USA.
  • Forrest WF; Department of Bioinformatics and Computational Biology, Genentech Inc, South San Francisco, 94080, CA, USA.
  • Behrens TW; Department of Bioinformatics and Computational Biology, Genentech Inc, South San Francisco, 94080, CA, USA.
  • Graham RR; Department of Bioinformatics and Computational Biology, Genentech Inc, South San Francisco, 94080, CA, USA.
  • Wuster A; Department of Human Genetics, Genentech Inc, South San Francisco, 94080, CA, USA.
Genes Immun ; 20(2): 172-179, 2019 02.
Article in En | MEDLINE | ID: mdl-29550837
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Placebo Effect / Clinical Trials, Phase III as Topic / Polymorphism, Single Nucleotide Type of study: Clinical_trials / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Genes Immun Year: 2019 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Placebo Effect / Clinical Trials, Phase III as Topic / Polymorphism, Single Nucleotide Type of study: Clinical_trials / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Genes Immun Year: 2019 Document type: Article