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A pilot study of ultra-deep targeted sequencing of plasma DNA identifies driver mutations in hepatocellular carcinoma.
Labgaa, Ismail; Villacorta-Martin, Carlos; D'Avola, Delia; Craig, Amanda J; von Felden, Johann; Martins-Filho, Sebastiao N; Sia, Daniela; Stueck, Ashley; Ward, Stephen C; Fiel, M Isabel; Mahajan, Milind; Tabrizian, Parissa; Thung, Swan N; Ang, Celina; Friedman, Scott L; Llovet, Josep M; Schwartz, Myron; Villanueva, Augusto.
Affiliation
  • Labgaa I; Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, USA.
  • Villacorta-Martin C; Department of Visceral Surgery, Lausanne University Hospital CHUV, Lausanne, Switzerland.
  • D'Avola D; Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, USA.
  • Craig AJ; Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, USA.
  • von Felden J; Liver Unit and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Clinica Universidad de Navarra, Pamplona, Spain.
  • Martins-Filho SN; Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, USA.
  • Sia D; Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, USA.
  • Stueck A; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Ward SC; Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, USA.
  • Fiel MI; Department of Pathology, University of Sao Paulo School of Medicine, Sao Paulo, Brazil.
  • Mahajan M; Department of Pathology and Laboratory Medicine, University Health Network, University of Toronto, Toronto, ON, Canada.
  • Tabrizian P; Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, USA.
  • Thung SN; Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, USA.
  • Ang C; Department of Pathology, Dalhousie University, Halifax, NS, Canada.
  • Friedman SL; Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, USA.
  • Llovet JM; Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, USA.
  • Schwartz M; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, USA.
  • Villanueva A; Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, USA.
Oncogene ; 37(27): 3740-3752, 2018 07.
Article in En | MEDLINE | ID: mdl-29628508
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Mutational Analysis / Carcinoma, Hepatocellular / High-Throughput Nucleotide Sequencing / Circulating Tumor DNA / Liver Neoplasms Limits: Adult / Aged / Humans / Male / Middle aged Language: En Journal: Oncogene Year: 2018 Document type: Article
Fulltext
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Mutational Analysis / Carcinoma, Hepatocellular / High-Throughput Nucleotide Sequencing / Circulating Tumor DNA / Liver Neoplasms Limits: Adult / Aged / Humans / Male / Middle aged Language: En Journal: Oncogene Year: 2018 Document type: Article