The Protective effect of P7C3 against DNA and neuron damage in rat pups with congenital hypothyroidism.

Dogan, Halef Okan; Alcigir, Mehmet Eray

Dogan, Halef Okan; Alcigir, Mehmet Eray.

Affiliation

Dogan HO; Department of Biochemistry, Faculty of Medicine, University of Cumhuriyet, Sivas, Turkey; Experimental Animal Laboratory, Faculty of Medicine, University of Cumhuriyet, Sivas, Turkey. Electronic address: hodogan@cumhuriyet.edu.tr.
Alcigir ME; Department of Pathology, Faculty of Veterinary Medicine, University of Ankara, Ankara, Turkey.

Biomed Pharmacother ; 99: 499-503, 2018 Mar.

Article in En | MEDLINE | ID: mdl-29665652

Subject(s)

Carbazoles/therapeutic use; Congenital Hypothyroidism/drug therapy; Congenital Hypothyroidism/pathology; DNA Damage; Neurons/pathology; Neuroprotection; Neuroprotective Agents/therapeutic use; 8-Hydroxy-2'-Deoxyguanosine; Animals; Carbazoles/pharmacology; Congenital Hypothyroidism/blood; Deoxyguanosine/analogs & derivatives; Deoxyguanosine/metabolism; Female; Male; Neurons/drug effects; Neurons/metabolism; Neuroprotection/drug effects; Neuroprotective Agents/pharmacology; Phosphopyruvate Hydratase/blood; Phosphopyruvate Hydratase/metabolism; Rats, Wistar; Thyroid Hormones/blood

Key words

Congenital hypothyroidism; DNA damage; NSE; P7C3; Rat

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / Carbazoles / Neuroprotective Agents / Congenital Hypothyroidism / Neuroprotection / Neurons Limits: Animals Language: En Journal: Biomed Pharmacother Year: 2018 Document type: Article

Fulltext

XML

PubMed Links

Search on Google