The Evaluation of BMI1 Posttranslational Modifications During Retinal Degeneration to Understand BMI1 Action on Photoreceptor Death Execution.

Mbefo, Martial K; Arsenijevic, Yvan

Mbefo, Martial K; Arsenijevic, Yvan.

Affiliation

Mbefo MK; Unit of Gene Therapy and Stem Cell Biology, Department of Ophtalmology, Jules-Gonin Eye Hospital, University of Lausanne, Lausanne, Switzerland.
Arsenijevic Y; Unit of Gene Therapy and Stem Cell Biology, Department of Ophtalmology, Jules-Gonin Eye Hospital, University of Lausanne, Lausanne, Switzerland. yvan.arsenijevic@fa2.ch.

Adv Exp Med Biol ; 1074: 359-365, 2018.

Article in En | MEDLINE | ID: mdl-29721964

Subject(s)

Eye Proteins/physiology; Photoreceptor Cells, Vertebrate/pathology; Polycomb Repressive Complex 1/metabolism; Protein Processing, Post-Translational; Proto-Oncogene Proteins/metabolism; Retinitis Pigmentosa/pathology; Animals; Apoptosis; Chromatin/chemistry; Chromatin/ultrastructure; DNA Fragmentation; DNA, Superhelical/chemistry; Disease Models, Animal; Eye Proteins/chemistry; Mice; Mice, Knockout; Mice, Mutant Strains; Models, Biological; Necrosis; Phosphorylation; Photoreceptor Cells, Vertebrate/metabolism; Polycomb Repressive Complex 1/chemistry; Polycomb Repressive Complex 1/deficiency; Polycomb Repressive Complex 1/genetics; Polycomb Repressive Complex 1/physiology; Protein Folding; Proto-Oncogene Proteins/chemistry; Proto-Oncogene Proteins/deficiency; Proto-Oncogene Proteins/genetics; RNA, Messenger/biosynthesis; RNA, Messenger/genetics

Key words

BMI1; Epigenetic; Phosphorylation; Polycomb repressive complexes; Posttranslational modifications; Rd1; Retinal degeneration

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Processing, Post-Translational / Retinitis Pigmentosa / Proto-Oncogene Proteins / Photoreceptor Cells, Vertebrate / Eye Proteins / Polycomb Repressive Complex 1 Type of study: Prognostic_studies Limits: Animals Language: En Journal: Adv Exp Med Biol Year: 2018 Document type: Article

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