Pregnancies with factor V deficiency: a case report and review of the literature.
Clin Exp Obstet Gynecol
; 44(2): 299-300, 2017.
Article
in En
| MEDLINE
| ID: mdl-29746045
ABSTRACT
CASE REPORT A 30-year-old Japanese nulliparous woman visited for pregnancy at 33 weeks with a massive ovarian tumor located in the pouch of Douglas. By preoperative screening, her prothrombin time (PT) and activated partial thromboplastin time (APTT) were prolonged, and her FV activity was significantly decreased to 4.8%. After prophylactic FFP 20 ml/kg was administered and her FV factor was 19.3%, cesarean delivery was performed, and her perioperative course was uneventful. One year later, she underwent a dilatation and evacuation because of a missed abortion, although prophylactic FFP was not administered. During a third pregnancy, after prophylactic FFP 20 ml/kg was administered and FV activity increased to 21.1%, elective cesarean delivery was performed, and her postoperative course was uneventful. CONCLUSION:
For surgical therapy or delivery, the goal of therapy is to maintain FV activity above 20%. It is particularly useful to administer prophylactic FFP.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Plasma
/
Pregnancy Complications, Hematologic
/
Cesarean Section
/
Factor V Deficiency
/
Obstetric Labor Complications
Type of study:
Diagnostic_studies
Limits:
Female
/
Humans
/
Pregnancy
Language:
En
Journal:
Clin Exp Obstet Gynecol
Year:
2017
Document type:
Article