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Ursodeoxycholate inhibits mast cell activation and reverses biliary injury and fibrosis in Mdr2-/- mice and human primary sclerosing cholangitis.
Meng, Fanyin; Kennedy, Lindsey; Hargrove, Laura; Demieville, Jennifer; Jones, Hannah; Madeka, Taronish; Karstens, Allen; Chappell, Kevin; Alpini, Gianfranco; Sybenga, Amelia; Invernizzi, Pietro; Bernuzzi, Francesca; DeMorrow, Sharon; Francis, Heather.
Affiliation
  • Meng F; Research, Central Texas Veterans Health Care System, Temple, TX, USA.
  • Kennedy L; Scott & White Digestive Disease Research Center, Baylor Scott & White Health, Temple, TX, USA.
  • Hargrove L; Medical Physiology, Texas A&M Health Science Center, Temple, TX, USA.
  • Demieville J; Research, Central Texas Veterans Health Care System, Temple, TX, USA.
  • Jones H; Medical Physiology, Texas A&M Health Science Center, Temple, TX, USA.
  • Madeka T; Research, Central Texas Veterans Health Care System, Temple, TX, USA.
  • Karstens A; Scott & White Digestive Disease Research Center, Baylor Scott & White Health, Temple, TX, USA.
  • Chappell K; Scott & White Digestive Disease Research Center, Baylor Scott & White Health, Temple, TX, USA.
  • Alpini G; Scott & White Digestive Disease Research Center, Baylor Scott & White Health, Temple, TX, USA.
  • Sybenga A; Scott & White Digestive Disease Research Center, Baylor Scott & White Health, Temple, TX, USA.
  • Invernizzi P; Research, Central Texas Veterans Health Care System, Temple, TX, USA.
  • Bernuzzi F; Scott & White Digestive Disease Research Center, Baylor Scott & White Health, Temple, TX, USA.
  • DeMorrow S; Medical Physiology, Texas A&M Health Science Center, Temple, TX, USA.
  • Francis H; Scott & White Digestive Disease Research Center, Baylor Scott & White Health, Temple, TX, USA.
Lab Invest ; 98(11): 1465-1477, 2018 11.
Article in En | MEDLINE | ID: mdl-30143751
Subject(s)
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ursodeoxycholic Acid / Cholagogues and Choleretics / Cholangitis, Sclerosing / Mast Cells Type of study: Clinical_trials / Observational_studies Limits: Animals / Humans Language: En Journal: Lab Invest Year: 2018 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ursodeoxycholic Acid / Cholagogues and Choleretics / Cholangitis, Sclerosing / Mast Cells Type of study: Clinical_trials / Observational_studies Limits: Animals / Humans Language: En Journal: Lab Invest Year: 2018 Document type: Article