Peak oxygen uptake cut-points to identify children at increased cardiometabolic risk - The PANIC Study.
Scand J Med Sci Sports
; 29(1): 16-24, 2019 Jan.
Article
in En
| MEDLINE
| ID: mdl-30230064
ABSTRACT
We aimed to develop cut-points for directly measured peak oxygen uptake ( V Ë O 2 peak ) to identify boys and girls at increased cardiometabolic risk using different scaling methods to control for body size and composition. Altogether 352 children (186 boys, 166 girls) aged 9-11 years were included in the analyses. We measured VÌO2peak directly during a maximal cycle ergometer exercise test and lean body mass (LM) by bioelectrical impedance. We computed a sex- and age-specific cardiometabolic risk score (CRS) by summing important cardiometabolic risk factors and defined increased cardiometabolic risk as >1 standard deviation above the mean of CRS. Receiver operating characteristics curves were used to detect VÌO2peak cut-points for increased cardiometabolic risk. Boys with VÌO2peak <45.8 mL kg body mass (BM)-1 min-1 (95% confidence interval [CI] = 45.1 to 54.6, area under the curve [AUC] = 0.86, P < 0.001) and <63.2 mL kg LM-1 min-1 (95% CI =52.4 to 67.5, AUC = 0.65, P = 0.006) had an increased CRS. Girls with VÌO2peak <44.1 mL kg BM-1 min-1 (95% CI = 44.0 to 58.6, AUC = 0.67, P = 0.013) had an increased CRS. VÌO2peak scaled by BM-0.49 and LM-0.77 derived from log-linear allometric modeling poorly predicted increased cardiometabolic risk in boys and girls. In conclusion, directly measured V Ë O 2 peak <45.8 mL kg BM-1 min-1 among boys and <44.1 mL kg BM-1 min-1 among girls were cut-points to identify those at increased cardiometabolic risk. Appropriately controlling for body size and composition reduced the ability of cardiorespiratory fitness to identify children at increased cardiometabolic risk.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Oxygen Consumption
/
Cardiovascular Diseases
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Exercise Test
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Cardiorespiratory Fitness
Type of study:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Child
/
Female
/
Humans
/
Male
Language:
En
Journal:
Scand J Med Sci Sports
Year:
2019
Document type:
Article