Control of mRNA splicing by noncoding intragenic RNA elements that evoke a cellular stress response.

Kaempfer, Raymond; Namer, Lise Sarah; Osman, Farhat; Ilan, Lena

Kaempfer, Raymond; Namer, Lise Sarah; Osman, Farhat; Ilan, Lena.

Affiliation

Kaempfer R; Department of Biochemistry and Molecular Biology, Faculty of Medicine, The Hebrew University, Jerusalem, Israel. Electronic address: kaempfer@hebrew.edu.
Namer LS; Department of Biochemistry and Molecular Biology, Faculty of Medicine, The Hebrew University, Jerusalem, Israel.
Osman F; Department of Biochemistry and Molecular Biology, Faculty of Medicine, The Hebrew University, Jerusalem, Israel.
Ilan L; Department of Biochemistry and Molecular Biology, Faculty of Medicine, The Hebrew University, Jerusalem, Israel.

Int J Biochem Cell Biol ; 105: 20-23, 2018 12.

Article in En | MEDLINE | ID: mdl-30282053

Subject(s)

RNA Splicing/genetics; RNA, Messenger/genetics; RNA, Messenger/metabolism; RNA, Untranslated/genetics; RNA, Untranslated/metabolism; Animals; Enzyme Activation; Eukaryotic Initiation Factor-2/metabolism; Globins/genetics; Humans; Models, Biological; Phosphorylation; Protein Biosynthesis; Spliceosomes/metabolism; Stress, Physiological; Tumor Necrosis Factor-alpha/genetics; eIF-2 Kinase/metabolism

Key words

Intragenic RNA activators of PKR; Stress signaling; eIF2α phosphorylation; mRNA splicing; mRNA translation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Messenger / RNA Splicing / RNA, Untranslated Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Int J Biochem Cell Biol Year: 2018 Document type: Article

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