Your browser doesn't support javascript.
loading
Evaluation of the agreement between TNM 7th and 8th in a population-based series of cutaneous melanoma.
Crocetti, E; Stanganelli, I; Mancini, S; Vattiato, R; Giuliani, O; Ravaioli, A; Balducci, C; Falcini, F; Pimpinelli, N.
Affiliation
  • Crocetti E; Romagna Cancer Registry, IRCCS, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Meldola, Italy.
  • Stanganelli I; Dermatology Unit, Department of Surgery and Translational Medicine, University of Florence Medical School, Florence, Italy.
  • Mancini S; Skin Cancer Unit, IRCCS, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Meldola, Italy.
  • Vattiato R; University of Parma, Parma, Italy.
  • Giuliani O; Romagna Cancer Registry, IRCCS, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Meldola, Italy.
  • Ravaioli A; Romagna Cancer Registry, IRCCS, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Meldola, Italy.
  • Balducci C; Romagna Cancer Registry, IRCCS, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Meldola, Italy.
  • Falcini F; Romagna Cancer Registry, IRCCS, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Meldola, Italy.
  • Pimpinelli N; Romagna Cancer Registry, IRCCS, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Meldola, Italy.
J Eur Acad Dermatol Venereol ; 33(3): 521-524, 2019 Mar.
Article in En | MEDLINE | ID: mdl-30317667
ABSTRACT

BACKGROUND:

The 8th edition of TNM has introduced new rules for staging cutaneous melanoma.

OBJECTIVE:

To compare TNM 7th and 8th editions in defining pathological stages of melanoma.

METHODS:

A population-based series of 1847 skin melanoma from Romagna cancer registry (Italy) incident during 2003-2012 has been used to measure the agreement (with Cohen's kappa) between TNM 8th and 7th editions in defining melanoma stage. Disease-specific survival has been computed for each stage according to TNM 7th and 8th.

RESULTS:

The agreement between the two TNM editions was quite good when considered on average (kappa = 70.7%), moderate for stage I (61.5%), nearly perfect for stage II (95.0%), but extremely poor for stage III (8.1%). The overall melanoma-specific observed survival was 90.8% at 5 year and 88.9% at 10 year with a strong prognostic effect of stage.

CONCLUSION:

TNM 8th edition introduces several changes which do not seem really helpful in addressing the care of stage I melanoma and may complicate the definition and comparability of stage III.
Subject(s)
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Melanoma / Neoplasm Staging Type of study: Prognostic_studies Limits: Humans Country/Region as subject: Europa Language: En Journal: J Eur Acad Dermatol Venereol Year: 2019 Document type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Melanoma / Neoplasm Staging Type of study: Prognostic_studies Limits: Humans Country/Region as subject: Europa Language: En Journal: J Eur Acad Dermatol Venereol Year: 2019 Document type: Article