In vivo cancer vaccination: Which dendritic cells to target and how?

Chiang, Cheryl Lai-Lai; Kandalaft, Lana E

Chiang, Cheryl Lai-Lai; Kandalaft, Lana E.

Affiliation

Chiang CL; Ludwig Institute for Cancer Research, and Department of Oncology, University Hospital of Lausanne (CHUV), Lausanne CH-1066, Switzerland.
Kandalaft LE; Ludwig Institute for Cancer Research, and Department of Oncology, University Hospital of Lausanne (CHUV), Lausanne CH-1066, Switzerland; Ovarian Cancer Research Center, University of Pennsylvania Medical Center, Smilow Translational Research Center 8th Floor, 186B, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA. Electronic address: lana.kandalaft@chuv.ch.

Cancer Treat Rev ; 71: 88-101, 2018 Dec.

Article in En | MEDLINE | ID: mdl-30390423

Subject(s)

Dendritic Cells/immunology; Immunotherapy/methods; Molecular Targeted Therapy/methods; Neoplasms/therapy; Toll-Like Receptors/agonists; Animals; Antineoplastic Agents/immunology; Antineoplastic Agents/pharmacology; Cancer Vaccines; Humans; Imiquimod/pharmacology; Langerhans Cells/cytology; Langerhans Cells/drug effects; Langerhans Cells/immunology; Lectins, C-Type/metabolism; Membrane Glycoproteins/metabolism; Receptors, Immunologic/metabolism; Skin/cytology; Toll-Like Receptor 3/agonists; Toll-Like Receptor 3/immunology; Toll-Like Receptor 7/agonists; Toll-Like Receptor 7/immunology; Toll-Like Receptor 8/agonists; Toll-Like Receptor 8/immunology; Toll-Like Receptor 9/agonists; Toll-Like Receptor 9/immunology

Key words

Anti-tumor responses; Cancer vaccination; Dendritic cells; Toll-like receptor; Toll-like receptor agonists; Tumor immunotherapy

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Full text: 1 Collection: 01-internacional Health context: 1_ASSA2030 Database: MEDLINE Main subject: Dendritic Cells / Toll-Like Receptors / Molecular Targeted Therapy / Immunotherapy / Neoplasms Limits: Animals / Humans Language: En Journal: Cancer Treat Rev Year: 2018 Document type: Article

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