A clickable caging group as a new platform for modular caged compounds with improved photochemical properties.
Chem Commun (Camb)
; 55(4): 451-454, 2019 Jan 03.
Article
in En
| MEDLINE
| ID: mdl-30451249
ABSTRACT
A 6-bromo-7-hydroxycoumarin-4-ylmethyl (Bhc) caged compound having a click-modifiable chemical handle was designed and synthesized. This molecule was applied to the synthesis of modular caged paclitaxels (PTXs) in which additional functional units could be easily installed. This system was used to prepare water-soluble caged PTXs with improved photolysis efficiencies.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Chem Commun (Camb)
Year:
2019
Document type:
Article