Ryanodine Receptor to Mitochondrial Reactive Oxygen Species Pathway Plays an Important Role in Chronic Human Immunodeficiency Virus gp120MN-Induced Neuropathic Pain in Rats.

Godai, Kohei; Takahashi, Keiya; Kashiwagi, Yuta; Liu, Ching-Hang; Yi, Hyun; Liu, Shue; Dong, Chuanhui; Lubarsky, David A; Hao, Shuanglin

Godai, Kohei; Takahashi, Keiya; Kashiwagi, Yuta; Liu, Ching-Hang; Yi, Hyun; Liu, Shue; Dong, Chuanhui; Lubarsky, David A; Hao, Shuanglin.

Affiliation

Godai K; From the Departments of Anesthesiology.
Takahashi K; From the Departments of Anesthesiology.
Kashiwagi Y; From the Departments of Anesthesiology.
Liu CH; From the Departments of Anesthesiology.
Yi H; From the Departments of Anesthesiology.
Liu S; From the Departments of Anesthesiology.
Dong C; Neurology, University of Miami Miller School of Medicine, Miami, Florida.
Lubarsky DA; From the Departments of Anesthesiology.
Hao S; From the Departments of Anesthesiology.

Anesth Analg ; 129(1): 276-286, 2019 07.

Article in En | MEDLINE | ID: mdl-30507840

Subject(s)

HIV Envelope Protein gp120; Hyperalgesia/chemically induced; Mitochondria/metabolism; Neuralgia/chemically induced; Peripheral Nerves/metabolism; Ryanodine Receptor Calcium Release Channel/metabolism; Spinal Cord Dorsal Horn/metabolism; Superoxides/metabolism; Animals; Disease Models, Animal; Hyperalgesia/metabolism; Hyperalgesia/physiopathology; Male; Neuralgia/metabolism; Neuralgia/physiopathology; Pain Threshold; Peripheral Nerves/physiopathology; Rats, Sprague-Dawley; Signal Transduction; Spinal Cord Dorsal Horn/physiopathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peripheral Nerves / HIV Envelope Protein gp120 / Superoxides / Ryanodine Receptor Calcium Release Channel / Spinal Cord Dorsal Horn / Hyperalgesia / Mitochondria / Neuralgia Limits: Animals Language: En Journal: Anesth Analg Year: 2019 Document type: Article

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