Anti-inflammatory role of TPCA-1 encapsulated nanosomes in porcine chondrocytes against TNF-&#945; stimulation.

Bhatti, Fazal Ur Rehman; Hasty, Karen A; Cho, Hongsik

Anti-inflammatory role of TPCA-1 encapsulated nanosomes in porcine chondrocytes against TNF-α stimulation.

Bhatti, Fazal Ur Rehman; Hasty, Karen A; Cho, Hongsik.

Affiliation

Bhatti FUR; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Research 151, VAMC, 1030 Jefferson Ave, Memphis, TN, 38104, USA.
Hasty KA; VA Medical Center, Memphis, TN, USA.
Cho H; Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Research 151, VAMC, 1030 Jefferson Ave, Memphis, TN, 38104, USA. khasty@uthsc.edu.

Inflammopharmacology ; 27(5): 1011-1019, 2019 Oct.

Article in En | MEDLINE | ID: mdl-30600473

Subject(s)

Amides/pharmacology; Anti-Inflammatory Agents/pharmacology; Chondrocytes/drug effects; Inflammation/drug therapy; Thiophenes/pharmacology; Tumor Necrosis Factor-alpha/metabolism; Animals; Basic Helix-Loop-Helix Transcription Factors/metabolism; Chondrocytes/metabolism; Collagen Type II/metabolism; Down-Regulation/drug effects; Drug Delivery Systems/methods; Gene Expression/drug effects; Inflammation/metabolism; Matrix Metalloproteinase 13/metabolism; Osteoarthritis/drug therapy; Osteoarthritis/metabolism; Signal Transduction/drug effects; Swine

Key words

Chondrocytes; Inflammation; Nanosomes; TNF-α; TPCA-1; p65 translocation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiophenes / Tumor Necrosis Factor-alpha / Chondrocytes / Amides / Inflammation / Anti-Inflammatory Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Inflammopharmacology Year: 2019 Document type: Article

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