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The histone methyltransferase DOT1L is required for proper DNA damage response, DNA repair, and modulates chemotherapy responsiveness.
Kari, Vijayalakshmi; Raul, Sanjay Kumar; Henck, Jana Maria; Kitz, Julia; Kramer, Frank; Kosinsky, Robyn Laura; Übelmesser, Nadine; Mansour, Wael Yassin; Eggert, Jessica; Spitzner, Melanie; Najafova, Zeynab; Bastians, Holger; Grade, Marian; Gaedcke, Jochen; Wegwitz, Florian; Johnsen, Steven A.
Affiliation
  • Kari V; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, 37075, Göttingen, Germany.
  • Raul SK; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, 37075, Göttingen, Germany.
  • Henck JM; Department of Biotechnology, Rama Devi Women's University, Bhubaneswar, 751022, India.
  • Kitz J; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, 37075, Göttingen, Germany.
  • Kramer F; Department of Pathology, University Medical Center Göttingen, 37075, Göttingen, Germany.
  • Kosinsky RL; Department of Medical Statistics, University Medical Center Göttingen, 37075, Göttingen, Germany.
  • Übelmesser N; Department of Computer Science, University Augsburg, 86159, Augsburg, Germany.
  • Mansour WY; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, 37075, Göttingen, Germany.
  • Eggert J; Institute of Molecular Oncology, Section for Cellular Oncology, Göttingen Center for Molecular Biosciences (GZMB) and University Medical Center, University of Göttingen, 37077, Göttingen, Germany.
  • Spitzner M; Laboratory of Radiobiology and Experimental Radiooncology, University Medical Center Hamburg-Eppendorf, 20246, Hamburg, Germany.
  • Najafova Z; Tumor Biology Department, National Cancer Institute, Cairo University, Cairo, 11796, Egypt.
  • Bastians H; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, 37075, Göttingen, Germany.
  • Grade M; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, 37075, Göttingen, Germany.
  • Gaedcke J; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, 37075, Göttingen, Germany.
  • Wegwitz F; Institute of Molecular Oncology, Section for Cellular Oncology, Göttingen Center for Molecular Biosciences (GZMB) and University Medical Center, University of Göttingen, 37077, Göttingen, Germany.
  • Johnsen SA; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, 37075, Göttingen, Germany.
Clin Epigenetics ; 11(1): 4, 2019 01 07.
Article in En | MEDLINE | ID: mdl-30616689

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rectal Neoplasms / Histones / Drug Resistance, Neoplasm / Methyltransferases Type of study: Prognostic_studies Limits: Humans Language: En Journal: Clin Epigenetics Year: 2019 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rectal Neoplasms / Histones / Drug Resistance, Neoplasm / Methyltransferases Type of study: Prognostic_studies Limits: Humans Language: En Journal: Clin Epigenetics Year: 2019 Document type: Article