The antinociceptive effect of anterior pretectal nucleus stimulation is mediated by distinct neurotransmitter mechanisms in descending pain pathways.

Genaro, Karina; Fabris, Débora; Prado, Wiliam A

Genaro, Karina; Fabris, Débora; Prado, Wiliam A.

Affiliation

Genaro K; Universidade de São Paulo, Departamento de Neurociências, Ribeirão Preto, SP, Brazil; Universidade de São Paulo, Departamento de Psicologia, Ribeirão Preto, SP, Brazil. Electronic address: kgenaro@uci.edu.
Fabris D; Universidade de São Paulo, Departamento de Neurociências, Ribeirão Preto, SP, Brazil; Universidade de São Paulo, Departamento de Psicologia, Ribeirão Preto, SP, Brazil.
Prado WA; Universidade de São Paulo, Departamento de Farmacologia, Ribeirão Preto, SP, Brazil; Universidade de São Paulo, Departamento de Psicologia, Ribeirão Preto, SP, Brazil.

Brain Res Bull ; 146: 164-170, 2019 03.

Article in En | MEDLINE | ID: mdl-30634015

Subject(s)

Pain Management/methods; Pain/metabolism; Pretectal Region/drug effects; Analgesia/methods; Analgesics, Opioid; Animals; Electric Stimulation; Male; Methysergide; N-Methylaspartate/pharmacology; Naloxone; Narcotic Antagonists/pharmacology; Neurotransmitter Agents/metabolism; Neurotransmitter Agents/pharmacology; Nociceptors/metabolism; Pain/physiopathology; Pain Measurement/drug effects; Pedunculopontine Tegmental Nucleus/drug effects; Pedunculopontine Tegmental Nucleus/metabolism; Pretectal Region/metabolism; Rats; Rats, Wistar

Key words

AP-7; Anterior pretectal nucleus; Lateral paragigantocellular nucleus; Mecamylamine; Methysergide; Naloxone; Tegmental pedunculopontine nucleus

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pain / Pain Management / Pretectal Region Limits: Animals Language: En Journal: Brain Res Bull Year: 2019 Document type: Article

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