Your browser doesn't support javascript.
loading
Development of bioactive gemcitabine-D-Lys6-GnRH prodrugs with linker-controllable drug release rate and enhanced biopharmaceutical profile.
Sayyad, Nisar; Vrettos, Eirinaios I; Karampelas, Theodoros; Chatzigiannis, Christos M; Spyridaki, Katerina; Liapakis, George; Tamvakopoulos, Constantin; Tzakos, Andreas G.
Affiliation
  • Sayyad N; Department of Chemistry, Section of Organic Chemistry and Biochemistry, Laboratory of Chemical Biology, University of Ioannina, Ioannina, GR-45110, Greece.
  • Vrettos EI; Department of Chemistry, Section of Organic Chemistry and Biochemistry, Laboratory of Chemical Biology, University of Ioannina, Ioannina, GR-45110, Greece.
  • Karampelas T; Division of Pharmacology-Pharmacotechnology, Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece.
  • Chatzigiannis CM; Department of Chemistry, Section of Organic Chemistry and Biochemistry, Laboratory of Chemical Biology, University of Ioannina, Ioannina, GR-45110, Greece.
  • Spyridaki K; Department of Pharmacology, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece.
  • Liapakis G; Department of Pharmacology, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece.
  • Tamvakopoulos C; Division of Pharmacology-Pharmacotechnology, Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, Athens, Greece.
  • Tzakos AG; Department of Chemistry, Section of Organic Chemistry and Biochemistry, Laboratory of Chemical Biology, University of Ioannina, Ioannina, GR-45110, Greece. Electronic address: atzakos@cc.uoi.gr.
Eur J Med Chem ; 166: 256-266, 2019 Mar 15.
Article in En | MEDLINE | ID: mdl-30716713
Subject(s)
Key words
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prodrugs / Gonadotropin-Releasing Hormone / Deoxycytidine / Drug Liberation / Lysine Limits: Animals / Humans Language: En Journal: Eur J Med Chem Year: 2019 Document type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prodrugs / Gonadotropin-Releasing Hormone / Deoxycytidine / Drug Liberation / Lysine Limits: Animals / Humans Language: En Journal: Eur J Med Chem Year: 2019 Document type: Article