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Mitochondrial Dysfunction in Neural Injury.
Zhao, Xiu-Yun; Lu, Mei-Hong; Yuan, De-Juan; Xu, De-En; Yao, Pei-Pei; Ji, Wen-Li; Chen, Hong; Liu, Wen-Long; Yan, Chen-Xiao; Xia, Yi-Yuan; Li, Shao; Tao, Jin; Ma, Quan-Hong.
Affiliation
  • Zhao XY; Institute of Neuroscience and Jiangsu Key Laboratory of Neuropsychiatric Diseases, Soochow University, Suzhou, China.
  • Lu MH; Department of Neurology and Suzhou Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou, China.
  • Yuan DJ; Institute of Neuroscience and Jiangsu Key Laboratory of Neuropsychiatric Diseases, Soochow University, Suzhou, China.
  • Xu DE; Department of Neurology and Suzhou Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou, China.
  • Yao PP; Institute of Neuroscience and Jiangsu Key Laboratory of Neuropsychiatric Diseases, Soochow University, Suzhou, China.
  • Ji WL; Department of Physiology, Liaoning Provincial Key Laboratory of Cerebral Diseases, Dalian Medical University, Dalian, China.
  • Chen H; Wuxi No. 2 People's Hospital, Wuxi, China.
  • Liu WL; Institute of Neuroscience and Jiangsu Key Laboratory of Neuropsychiatric Diseases, Soochow University, Suzhou, China.
  • Yan CX; Department of Neurology and Suzhou Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou, China.
  • Xia YY; Institute of Neuroscience and Jiangsu Key Laboratory of Neuropsychiatric Diseases, Soochow University, Suzhou, China.
  • Li S; Department of Neurology and Suzhou Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou, China.
  • Tao J; Institute of Neuroscience and Jiangsu Key Laboratory of Neuropsychiatric Diseases, Soochow University, Suzhou, China.
  • Ma QH; Department of Neurology and Suzhou Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Front Neurosci ; 13: 30, 2019.
Article in En | MEDLINE | ID: mdl-30778282
ABSTRACT
Mitochondria are the double membrane organelles providing most of the energy for cells. In addition, mitochondria also play essential roles in various cellular biological processes such as calcium signaling, apoptosis, ROS generation, cell growth, and cell cycle. Mitochondrial dysfunction is observed in various neurological disorders which harbor acute and chronic neural injury such as neurodegenerative diseases and ischemia, hypoxia-induced brain injury. In this review, we describe how mitochondrial dysfunction contributes to the pathogenesis of neurological disorders which manifest chronic or acute neural injury.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Front Neurosci Year: 2019 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Front Neurosci Year: 2019 Document type: Article