EGF promotes HIF-1&#945; expression in colorectal cancer cells and tumor metastasis by regulating phosphorylation of STAT3.

Zhao, F-L; Qin, C-F

EGF promotes HIF-1α expression in colorectal cancer cells and tumor metastasis by regulating phosphorylation of STAT3.

Zhao, F-L; Qin, C-F.

Affiliation

Zhao FL; Department of Hernia and Abdominal Wall Surgery, Beijing ChaoYang Hospital, Capital Medical University, Beijing, China. qin_pku2012@bjmu.edu.cn.

Eur Rev Med Pharmacol Sci ; 23(3): 1055-1062, 2019 Feb.

Article in En | MEDLINE | ID: mdl-30779072

Subject(s)

Epidermal Growth Factor/physiology; Gene Expression Regulation, Neoplastic/physiology; Hypoxia-Inducible Factor 1, alpha Subunit/biosynthesis; STAT3 Transcription Factor/metabolism; Carcinogenesis/drug effects; Cell Line, Tumor; Cell Movement/drug effects; Cell Proliferation/drug effects; Epidermal Growth Factor/pharmacology; Humans; Niclosamide/pharmacology; Phosphorylation/physiology; RNA, Small Interfering/pharmacology; STAT3 Transcription Factor/antagonists & inhibitors; Signal Transduction/drug effects; Up-Regulation/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Neoplastic / Epidermal Growth Factor / STAT3 Transcription Factor / Hypoxia-Inducible Factor 1, alpha Subunit Limits: Humans Language: En Journal: Eur Rev Med Pharmacol Sci Year: 2019 Document type: Article

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