ahr2, But Not ahr1a or ahr1b, Is Required for Craniofacial and Fin Development and TCDD-dependent Cardiotoxicity in Zebrafish.

Souder, Jaclyn P; Gorelick, Daniel A

Souder, Jaclyn P; Gorelick, Daniel A.

Affiliation

Souder JP; Medical Scientist Training Program & Department of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, Alabama, 35294.
Gorelick DA; Department of Molecular and Cellular Biology, Center for Precision Environmental Health, Baylor College of Medicine, Houston, Texas, 77030.

Toxicol Sci ; 170(1): 25-44, 2019 07 01.

Article in En | MEDLINE | ID: mdl-30907958

Subject(s)

Animal Fins/growth & development; Cardiotoxicity/etiology; Craniofacial Abnormalities/genetics; Polychlorinated Dibenzodioxins/toxicity; Receptors, Aryl Hydrocarbon/metabolism; Skull/growth & development; Zebrafish Proteins/metabolism; Animal Fins/drug effects; Animals; Cardiotoxicity/genetics; Cardiotoxicity/metabolism; Craniofacial Abnormalities/metabolism; Embryo, Nonmammalian; Female; Male; Receptors, Estrogen/antagonists & inhibitors; Receptors, Estrogen/metabolism; Skull/drug effects; Skull/metabolism; Water Pollutants, Chemical/toxicity; Zebrafish

Key words

agents, aquatic toxicology; aryl hydrocarbon; gene expression/regulation, receptor; dioxin; endocrine toxicology; environmental toxicology, nonmammalian species; environmental toxicology, receptor; gene expression/regulation, endocrine; nuclear hormone; receptor

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skull / Receptors, Aryl Hydrocarbon / Craniofacial Abnormalities / Zebrafish Proteins / Animal Fins / Cardiotoxicity / Polychlorinated Dibenzodioxins Limits: Animals Language: En Journal: Toxicol Sci Year: 2019 Document type: Article

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